A Pharmacokinetic and Pharmacogenetic Study in Patients Receiving Sulfamethoxazole-trimethoprim Therapy
NCT02045160 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 1000
Last updated 2014-08-04
Summary
In this study, we aim to investigate the incidence of the adverse reactions, the effectiveness and the gene polymorphism associated with the plasma level of sulfamethoxazole-trimethoprim and their metabolites (including N4-acetyl-sulfamethoxazole, sulfamethoxazole hydroxylamine and sulfamethoxazole-nitroso). And we also aim to investigate the factors associated with the sulfamethoxazole-trimethoprim induced acute psychosis.
Conditions
- Pneumocystis Jirovecii Pneumonia
Sponsors & Collaborators
-
National Taiwan University Hospital
lead OTHER
Eligibility
- Min Age
- 20 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2014-01-31
- Primary Completion
- 2017-12-31
- Completion
- 2017-12-31
Countries
- Taiwan
Study Locations
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