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Meal-Exercise Challenge and Physical Activity Reduction Impact on Immunity and Inflammation

NCT02027675 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 42

Last updated 2015-04-29

No results posted yet for this study

Summary

In a society where exercise is prescribed by physicians to increase physical condition, improve dietary habits and reduce cardiovascular risk, the impact of exercise, acute or chronic, and diet in inflammation and immunity is unknown. Specific populations can have different responses towards acute and chronic exercise. Moreover specific conditions, like the type of meal ingested, can interfere with these responses. The true effect of pre-competitive meal exercise in the immunity and inflammatory response is unknown. Acute physical inactivity periods, commonly happens during daily life, related to work or acute illness. New evidence points out that it induces immediate metabolic and endocrinological changes, these can might also be associated with changes in immune response.

Aims of this project are:

1. to assess the effect of the precompetitive meal on the inflammatory, neuro-immune and metabolic response to exercise;
2. to assess the effects of sedentary behaviour on inflammatory, neuro-immune and metabolic response;
3. to assess differences in changes between healthy, asthmatic and obese subjects

Conditions

Interventions

OTHER

High fat poor micronutrient meal

The meal will be prepared by a team of nutritionist in order to comply with the demand characteristics of an high fat poor micronutrient meal.

OTHER

Mediterranean meal

The meal will be prepared by a team of nutritionist in order to comply with the demand characteristics of an Mediterranean meal

Sponsors & Collaborators

  • Universidade do Porto

    lead OTHER

Principal Investigators

  • Diana Silva, MD · Faculty of Medicine of Porto University

  • Rita Moreira · Faculty of Nutrition and Food Sciences of the University of Porto

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
35 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2014-04-30
Primary Completion
2014-09-30
Completion
2014-09-30

Countries

  • Portugal

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02027675 on ClinicalTrials.gov