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MSCs For Treatment of Azoospermic Patients

NCT02025270 · Status: COMPLETED · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 100

Last updated 2023-03-01

No results posted yet for this study

Summary

In this study, we performed autologous BMDMSC transplantation to the testis of Azoospermic patients in a trial to enhance and activate the spermatogonial stem cells of the testis and aiming to produce motile sperm.

Conditions

  • Male Infertility

Interventions

BIOLOGICAL

Stem Cells

60 ml of bone marrow will aspirated and used for stem cells isolation. Then stem cells will cultured using autologous serum, characterized and prepared using GMP rules and finally injected into rete testis.

Sponsors & Collaborators

  • Cairo University

    collaborator OTHER

  • Al-Azhar University

    lead OTHER

Principal Investigators

  • Taimour M Khalifa, MD Professor · Al-Azhar University

  • Sayed Bakry, PhD · Al-Azhar University

  • Saad Moneer, MSc · Al-Azhar University

  • Ahmed Kadeh, MSc · Al-Azhar University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
SINGLE_GROUP

Eligibility

Min Age
20 Years
Max Age
50 Years
Sex
MALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2012-10-15
Primary Completion
2016-10-15
Completion
2022-12-20

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02025270 on ClinicalTrials.gov