Decompressive Cervical Surgery and Hypertension
NCT02016768 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 50
Last updated 2020-01-13
Summary
There is a relationship between CSM and hypertension, probably a cause/effect relationship, and investigators term this type of hypertension "cervicogenic hypertension". Abnormally functioning serotonergic pacemaker cells in the dorsal raphe nucleus inappropriately activate and inhibit parts of the central and autonomic nervous systems as part of a chronic stress response, which causes hypertension and migraine. This theory is now being expanded to encompass both CSM and essential hypertension, the idea being that these two conditions are intimately related.
Conditions
- Myelopathy, Compressive
- Hypertension
Interventions
- PROCEDURE
-
decompressive cervical surgery
To make decompressive cervical surgery, either anterior cervical discectomy and fusion or posterior laminoplasty on the patients suffering from cervical spondylotic myelopathy and hypertension.
Sponsors & Collaborators
-
Peking University
collaborator OTHER -
Peking University First Hospital
lead OTHER
Principal Investigators
-
Hong Liu, Master · Peking Unversity First Hospital
Eligibility
- Min Age
- 18 Years
- Max Age
- 84 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2014-06-30
- Primary Completion
- 2016-12-31
- Completion
- 2016-12-31
Countries
- China
Study Locations
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