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DeHydration: Assessing Kids Accurately

NCT02007733 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 1396

Last updated 2023-02-23

No results posted yet for this study

Summary

Diarrhea is the second leading cause of death in children worldwide, and accurately assessing dehydration status remains a crucial step in preventing morbidity and mortality from this disease. While children with severe dehydration require immediate treatment with intravenous fluids, children with mild to moderate dehydration have a significant reduction in hospital length of stay and fewer adverse events when treated with relatively inexpensive oral rehydration solution (ORS). While several clinical scales have been developed for assessing dehydration in children, these scales have never been prospectively validated in a low-income country setting, where the vast majority of diarrhea morbidity and mortality occurs in children.

The investigators hypothesize that new clinical and ultrasound-based tools will improve the diagnosis of severe dehydration in children with diarrhea in low-income countries, reducing the morbidity and mortality that occurs as a result of under-diagnosis of severe dehydration as well as the adverse events and inappropriate utilization of scarce resources that occurs as a result of over-diagnosis of severe dehydration.

Conditions

  • Severe Dehydration

Interventions

OTHER

Serial Weights

We will collect serial weights on all children enrolled in this study.

OTHER

IVC/Aorta Ultrasound

We will perform an ultrasound assessment of the IVC and Aorta size in each child enrolled.

OTHER

Clinical Assessment

We will perform a clinical assessment of dehydration status in each child enrolled in the study, as well as collect data on mid-upper arm circumference, length, symptoms and demographic information.

Sponsors & Collaborators

  • Fogarty International Center of the National Institute of Health

    collaborator NIH

  • International Centre for Diarrhoeal Disease Research, Bangladesh

    collaborator OTHER

  • Rhode Island Hospital

    lead OTHER

Principal Investigators

  • Adam C. Levine, MD, MPH · Brown University

Eligibility

Min Age
1 Month
Max Age
60 Months
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-02-28
Primary Completion
2015-05-31
Completion
2015-06-30

Countries

  • Bangladesh

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02007733 on ClinicalTrials.gov