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Anesthesia and Circulating Tumor Cells in Breast Cancer

NCT02005770 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 221

Last updated 2020-04-14

No results posted yet for this study

Summary

Serious concern about the role of anesthesia in tumor recurrence has considerably risen over years, but the lack of surrogate markers for tumor spreading made trials addressing this issue difficult to realize. In breast cancer patients CTC positivity has been recently recognized as an independent prognostic factor. In this respect, we postulated that in a first step changes in the number of CTC after general anesthesia would help to determine the effect of anesthesia on this tumor marker.

Conditions

  • Female Breast Carcinoma

Interventions

DRUG

Sevoflurane

DRUG

Propofol

Sponsors & Collaborators

  • University of Zurich

    lead OTHER

Principal Investigators

  • Beatrice Beck Schimmer, Prof MD · University Hospital Zurich, Institute of Anesthesiology

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
85 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-03-31
Primary Completion
2018-04-30
Completion
2018-04-30

Countries

  • Switzerland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02005770 on ClinicalTrials.gov