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Phenotype/Genotype Correlation in a Family With Early Onset Osteoarthritis

NCT01999166 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 5

Last updated 2025-07-30

No results posted yet for this study

Summary

This study will investigate the genes responsible for osteoarthritis. Individuals with osteoarthritis known or suspected to be caused by a gene mutation (change) may be eligible for this study. Family members may also participate.

Patients will talk with investigators who will explain the study and its possible implications for the patient and family and answer questions. The patient's medical records will be reviewed, a personal and family history will be taken, and a physical examination will be done. Two procedures may be done including blood sampling (which will be used for DNA (genetic) studies) and X-rays (to define osteoarthritis grade).

If no known mutations responsible for osteoarthritis will be detected, participating family members will be interviewed by telephone about their personal and family health history and will have a blood sample drawn for DNA testing, and X-rays.

Conditions

Interventions

RADIATION

radiography (X-ray)

GENETIC

DNA sampling

Sponsors & Collaborators

  • University Hospital, Caen

    lead OTHER

Principal Investigators

  • Christian MARCELLI · University Hospital, Caen

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-10-07
Primary Completion
2021-12-31
Completion
2022-12-31

Countries

  • France

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01999166 on ClinicalTrials.gov