Rhinopharyngeal Retrograde Clearance is Effective to Adequate Upper Airways Function in Adults
NCT01976039 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 24
Last updated 2018-04-19
Summary
Professionals working in polluted areas may present increased clinical airways symptoms and dysfunction. Rhinopharyngeal retrograde clearance (RRC) has been used to improve mucus clearance in infants with bronchitis and bronchiolitis, and instillation the nasal cavity with saline has been used to reduce nasal inflammation in rhinitis and sinusopathies. The aim of this study was to assess the effects of RRC and RCC combined with saline (RRC+S) on nasal mucociliary clearance (MCC), mucus surface property, cellularity and airways symptoms in professional motorcyclists.
Conditions
- Nasal Obstruction
- Exposure to Pollution
Interventions
- OTHER
-
rhinopharyngeal retrograde clearance (RRC)
The rhinopharyngeal retrograde clearance is a respiratory physical therapy technique that uses a forced inspiratory maneuver to clear the nasopharynx with the aid of saline instillation
Sponsors & Collaborators
-
Fundação de Amparo à Pesquisa do Estado de São Paulo
collaborator OTHER_GOV -
Conselho Nacional de Desenvolvimento Científico e Tecnológico
collaborator OTHER_GOV -
University of Sao Paulo
lead OTHER
Principal Investigators
-
Naomi K Nakagawa, PhD · University of Sao Paulo
-
Paulo HN Saldiva, PhD · University of Sao Paulo
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- TRIPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 45 Years
- Sex
- MALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2012-07-31
- Primary Completion
- 2012-08-31
- Completion
- 2012-08-31
Countries
- Brazil
Study Locations
More Related Trials
-
Oxymetazoline Hydrochloride in Combination With Nasal Glucocorticosteroid for Perennial Allergic and Non-allergic Rhinitis in Subjects With Persistent Nasal Congestion
NCT00584662 ·Status: TERMINATED ·Phase: NA
-
Impact of External Nasal Dilator on the Rhinogram
NCT01411969 ·Status: COMPLETED
-
Efficacy of Two Nasal Products for Decongestion and Mucus Fluidification
NCT04230993 ·Status: COMPLETED ·Phase: NA
-
Topical Irrigation Therapy for CRS
NCT02630472 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
A Randomized Double Dummy Double Blind Dose Determining Place-bo Controlled Study to Evaluate Efficacy of Investigational Product E-RH-06 at 2 Dose Levels for the Metabolic Management of Chronic or Recurrent, Non-infective Nasal Congestion With-or-without Rhinorrhea.
NCT01546662 ·Status: UNKNOWN ·Phase: NA
-
PMCF to Assess Real-life Usage Effectiveness, Safety and Patient Satisfaction of a Range of Hypertonic Seawater-based Decongestant Nasal Sprays
NCT06104332 ·Status: COMPLETED
-
Proof of Concept of Remote Management of Chronic Inflammatory Airway Diseases for Patient Empowerment
NCT06217419 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Pediatric Chronic Rhinosinusitis in Asthmatic Children
NCT06194097 ·Status: WITHDRAWN ·Phase: NA
-
Immediate Effect of Proponent-Nasal-Spray on Unspecific Discomfort in the Nose
NCT03251066 ·Status: COMPLETED ·Phase: NA
-
Assessement of Effectiveness of Seawater Nasal Sprays on Sinonasal Symptoms
NCT07262450 ·Status: RECRUITING ·Phase: NA
-
SinuSys Patency of Frontal Recess and Sphenoid Sinus Ostia Study
NCT02463279 ·Status: COMPLETED ·Phase: NA
-
Effects of Osteopathic Manipulative Treatment in Chronic Non-allergic Rhinosinusitis
NCT04420052 ·Status: WITHDRAWN ·Phase: NA
-
Botulinum Toxin Type A Block of the Sphenopalatine Ganglion in Chronic Rhinosinusitis With Nasal Polyposis
NCT02784262 ·Status: COMPLETED ·Phase: PHASE2
-
Evaluation of Efficacy of Platelet Rich Plasma as Anew Modality for Treatment of Atrophic Rhinitis
NCT04717960 ·Status: UNKNOWN ·Phase: NA
-
Market Potential of Carbon Dioxide Nasal Spray
NCT02113449 ·Status: COMPLETED ·Phase: PHASE2
-
Nanoparticles in Nasal Mucosa
NCT02270125 ·Status: COMPLETED
-
Impact of Chronic Rhinosinusitis on the Index of Ciliary Beat Efficiency Using Fluorescent Nanosticks: (R-IMPAC)
NCT04191590 ·Status: WITHDRAWN ·Phase: NA
-
Upper Airway Inflammation and Olfaction: Mechanisms of Loss and Recovery
NCT06776042 ·Status: RECRUITING ·Phase: NA
-
Treatment of Allergic Rhinitis and Chronic Polypous Rhinosinusitis With Olfactory Mucosa-derived Mesenchymal Stem Cells
NCT05167552 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Single-step Functional Sinus Endoscopy and Transoral Surgery
NCT06130176 ·Status: RECRUITING ·Phase: NA
-
Effects of Radiofrequency Ablation of Posterior Nasal Nerves on Inflammatory Cytokines, Peak Nasal Inspiratory Flow, and Nasal Blood Flow in Patients With Chronic Rhinitis
NCT05648565 ·Status: COMPLETED ·Phase: NA
-
Inferior Turbinate Surgery in Rhinoseptoplasty: a Randomized Clinical Trial With Quality of Life Outcomes
NCT01457638 ·Status: COMPLETED ·Phase: NA
-
A Study of Luffa Operculate Nasal Solution 5mg/mL Compared With Saline (NaCl 09%) for the Relief of Nasal Obstruction
NCT01248325 ·Status: UNKNOWN ·Phase: PHASE3
-
Posterior Nasal Nerve Combined with Anterior Ethmoid Neurotomy for Idiopathic Rhinitis
NCT06870292 ·Status: RECRUITING ·Phase: NA
-
Study of CM326 in Participants With Chronic Rhinosinusitis With Nasal Polyposis
NCT06372678 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2