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The Effect of Chronic Anemia on Safety Period of Tracheal Intubation in Gynecology Patients

NCT01968525 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 45

Last updated 2013-10-24

No results posted yet for this study

Summary

1. Every individual receiving a general anesthetic is at potential risk for developing a ''cannot intubate-cannot ventilate'' situation following anesthetic induction.
2. Building up of oxygen reserves assumes great significance as this provides a longer duration of non-hypoxic apnea should one be faced with an unanticipated difficult airway.
3. The main physiological functions of red blood cell hemoglobin are to deliver oxygen to the peripheral tissues.
4. During anemia, a reduction in blood oxygen content occurs as a result of reduced Hb while arterial oxygenation and oxyhemoglobin saturation remain high.
5. Previous studies about the duration of non-hypoxic apnoea focus on methods to improve the safety period of tracheal intubation.
6. To our knowledge, there is no literature about the duration of non-hypoxic apnoea of anemia patients.
7. The aim of this study was to assess the effect of chronic anemia on the duration of non-hypoxic apnoea during induction of anaesthesia.

Conditions

  • Chronic Anemia

Interventions

BIOLOGICAL

pre-oxygen

3 min of preoxygenation before anesthesia induction.

Sponsors & Collaborators

  • Fudan University

    lead OTHER

Principal Investigators

  • Guiqi Geng, PhD · Department of anesthesiology, obstetrics and genecology hospital, FuDan university

Study Design

Allocation
RANDOMIZED
Purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
45 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2013-04-30
Primary Completion
2013-09-30
Completion
2013-09-30

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01968525 on ClinicalTrials.gov