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Defining the Basis of Fibromuscular Dysplasia (FMD)

NCT01967511 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 600

Last updated 2025-09-29

No results posted yet for this study

Summary

The purpose of this study has evolved and expanded since its inception. Originally the intent was to establish the functional, molecular and genetic profile of fibroblasts from Fibromuscular Dysplasia (FMD) patients as compared to carefully matched control subjects. While this remains among the objectives, the study has been expanded to undertake a fully powered cross-tissue systems genetics analysis of FMD, and now also the related arteriopathies spontaneous coronary artery dissection (SCAD) and cervical artery dissection (CvAD). The overall objective is to disclose the core biologic mechanisms of these disorders.

Conditions

  • Fibromuscular Dysplasia
  • Spontaneous Coronary Artery Dissection
  • Cervical Artery Dissection

Sponsors & Collaborators

Principal Investigators

  • Jason Kovacic, MD, PhD · Icahn School of Medicine at Mount Sinai

  • Jeffrey Olin, DO · Icahn School of Medicine at Mount Sinai

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2013-10-31
Primary Completion
2030-12-31
Completion
2030-12-31

Countries

  • United States

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01967511 on ClinicalTrials.gov