Efficacy and Neural Basis of Music-based Neurological Rehabilitation for Traumatic Brain Injury

Summary

Traumatic brain injury (TBI) is one of the leading causes of serious, life-long disability among adolescents and young adults. Especially the cognitive, emotional, and motors deficits caused by TBI often impair everyday psychosocial functioning, quality of life and ability to work. The purpose of the study is to determine the long-term effect of music-based rehabilitation on cognitive, motor, emotional, and social recovery after TBI in adolescents and young adults, and to study the neural mechanisms that underlie behavioural recovery and the efficacy of music.

Conditions

• Traumatic Brain Injury (TBI)

Interventions

BEHAVIORAL

Music-based Neurological Rehabilitation (MBNR)

Music-based Neurological Rehabilitation (MBNR) will involve 10 weeks of individual training (30 sessions, 1 hour per session, 3 days per week) given by a trained music therapist. The MBNR protocol utilizes structured cognitive-motor training with drums (drum set, djembe drums) and creative musical expression (music playing, song writing) with piano that are geared towards engaging and training attention, executive functions, working memory, and upper-extremity functions and for enhancing emotional self-expression, adjustment, and mood after TBI.

OTHER

Standard Care (SC)

Standard Care (SC) consists of other types of conventional rehabilitation (physical therapy, occupational therapy, speech therapy, and/or neuropsychological rehabilitation) and medical care for TBI that the patients receive in Finnish private or public health care.

Sponsors & Collaborators

• Helsinki University Central Hospital

  collaborator OTHER

• Hospital District of Helsinki and Uusimaa

  collaborator OTHER

• University of Jyvaskyla

  collaborator OTHER

• Åbo Akademi University

  collaborator OTHER

• University of Barcelona

  collaborator OTHER

• University of Virginia

  collaborator OTHER

• Validia Rehabilitation Helsinki

  collaborator UNKNOWN

• University of Helsinki

  lead OTHER

Principal Investigators

• Teppo Sarkamo, PhD · University of Helsinki

• Mari Tervaniemi, PhD · University of Helsinki

• Anne Vehmas, MD · Kapyla Rehabilitation Centre, Helsinki, Finland

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Model

CROSSOVER

Eligibility

Min Age

16 Years

Max Age

60 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2014-03-31

Primary Completion

2017-12-31

Completion

2018-12-31

Countries

• Finland

Study Locations