Preventing Depression in People With Epilepsy: an Extension of Project UPLIFT

Summary

Project UPLIFT, a home-based treatment for depression in people with epilepsy, was designed to be delivered to groups by telephone or Web. The Project UPLIFT intervention materials were demonstrated to be effective in treating depression among people with epilepsy in Georgia. This project will assess whether the materials are also effective for preventing depression among people with epilepsy, and will extend the project beyond Georgia to Michigan, Texas, and Washington.

Conditions

• Epilepsy
• Depressive Symptoms
• Depression
• Seizure Disorder

Interventions

BEHAVIORAL

Project UPLIFT

Developed for home-based treatment of depression in people with epilepsy, Project UPLIFT is based upon Mindfulness-based Cognitive Therapy for depression. It includes 8 modules, group-delivered by either telephone or Web. Trainees and people with epilepsy co-facilitate the groups, supervised by a licensed mental health professional.The co-facilitators are trained and supervised by the Principal Investigator, a Georgia-licensed clinical psychologist and Associate Professor of Behavioral Science and of Epidemiology in public health. Activities are designed to increase knowledge about depression; monitoring, challenging, and changing thoughts; coping and relaxing; attention and mindfulness; focusing on pleasure; the importance of reinforcement, and preventing relapse.

Sponsors & Collaborators

• University of Michigan

  collaborator OTHER

• University of Washington

  collaborator OTHER

• The University of Texas Health Science Center, Houston

  collaborator OTHER

• National Institute on Minority Health and Health Disparities (NIMHD)

  collaborator NIH

• Emory University

  lead OTHER

Principal Investigators

• Nancy J Thompson, MPH, PhD · Emory University

Study Design

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

NONE

Model

CROSSOVER

Eligibility

Min Age

21 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2009-10-31

Primary Completion

2011-12-31

Completion

2012-06-30

Countries

• United States

Study Locations