MedTrace Logo

Sodium Chloride and Protein-Bound Toxin Removal in Hemodiafiltration

NCT01923961 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 8

Last updated 2019-01-16

Study results available
· View outcomes & findings →

Summary

An increase of the free fraction may allow a better removal of of protein-bound uremic toxins during dialysis. During predilution hemodiafiltration, the sodium chloride (NaCl) concentration will be increased in the infusion fluid at a target NaCl concentration and the effect on the removal of protein-bound toxins will be determined. Comparisons will be made to standard hemodialysis and hemodiafiltration.

Conditions

  • End-stage Renal Disease

Interventions

PROCEDURE

HDF NaCl

PROCEDURE

Hemodialysis

PROCEDURE

Standard Predilution Hemodiafiltration

Sponsors & Collaborators

  • EXcorLab GmbH

    lead OTHER

Principal Investigators

  • Detlef H Krieter, MD · Wuerzburg University Hospital

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2013-08-31
Primary Completion
2015-03-30
Completion
2015-08-10

Countries

  • Germany

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01923961 on ClinicalTrials.gov