MedTrace Logo

Impact of a Non-Drug Choice on Cocaine Reinforcement

NCT01906346 · Status: COMPLETED · Phase: EARLY_PHASE1 · Type: INTERVENTIONAL · Enrollment: 9

Last updated 2019-05-17

Study results available
· View outcomes & findings →

Summary

Cocaine-use disorders continue to be a significant public health concern, yet no effective medications have been identified. The goal of this study is to establish a research platform for the development of medications for treatment of cocaine abuse and dependence. This study will incorporate self-administration procedures and a non-drug alternative reinforcer, which is hypothesized to reduce the reinforcing effects of cocaine.

Conditions

  • Cocaine Dependence

Interventions

DRUG

Cocaine

Three active doses of cocaine will be made available for self-administration during experimental sessions.

DRUG

Placebo

Placebo cocaine will be made available for self-administration during experimental sessions.

Sponsors & Collaborators

  • Joshua A. Lile, Ph.D.

    lead OTHER

Principal Investigators

  • Joshua A Lile, Ph.D · University of Kentucky

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
21 Years
Max Age
45 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-01-31
Primary Completion
2015-06-30
Completion
2015-06-30

Countries

  • United States

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01906346 on ClinicalTrials.gov