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Surgery in Chronic Cough GERD Related

NCT01899183 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 67

Last updated 2013-07-15

No results posted yet for this study

Summary

The effectiveness of surgical fundoplication in treating classical reflux symptoms is well documented, but the role of surgery in alleviating extra-esophageal symptoms allegedly secondary to gastro-esophageal reflux disease (GORD) is far to be assessed.

The effectiveness of anti-reflux surgery on extra-esophageal reflux symptoms varies from 15% to 95%; the spread of these data is largely attributable to disparate study design and methodology, patient selection, and outcome metrics.

In order to assess whether anti-reflux surgery may have beneficial effects on chronic cough allegedly secondary to GERD and to eventually identify the preoperative clinical profile which could predict those positive effects, we considered two groups of patients presenting with 1) GERD associated to chronic cough, 2), typical GERD who underwent anti-reflux surgery.

Conditions

  • GERD

Interventions

PROCEDURE

Anti-reflux Surgery

Nissen Fundoplication; Collis Gastroplasty

Sponsors & Collaborators

  • University of Bologna

    lead OTHER

Principal Investigators

  • Sandro Mattioli, MD · Departement of Medical and Surgical Sciences University of Bologna

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
1995-01-31
Primary Completion
2010-12-31
Completion
2012-01-31

Countries

  • Italy

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01899183 on ClinicalTrials.gov