Interpersonal Psychotherapy for Treatment Resistant Depression

Summary

The purpose of this study is to determine whether combination of antidepressant drugs plus interpersonal psychotherapy is superior to antidepressant drugs alone in treatment resistant depression.

Conditions

• Treatment Resistant Depression

Interventions

OTHER

IPT+ antidepressant drugs

16 sessions of interpersonal psychotherapy plus antidepressant drugs.

DRUG

fluoxetine

Antidepressant drugs, clinician´s free choice oriented by guidelines. Monotherapy or combinations are allowed

DRUG

sertraline

DRUG

paroxetine

DRUG

Citalopram

DRUG

escitalopram

DRUG

fluvoxamine

DRUG

Venlafaxine

DRUG

Duloxetine

DRUG

Bupropion

DRUG

Lithium

DRUG

Risperidone

DRUG

tranylcypromine

DRUG

Imipramine

DRUG

amitriptyline

DRUG

Clomipramine

DRUG

nortriptyline

DRUG

trazodone

DRUG

Mirtazapine

DRUG

sulpiride

Sponsors & Collaborators

• Hospital de Clinicas de Porto Alegre

  lead OTHER

Principal Investigators

• Marcelo PA Fleck, MD,PhD · Federal University of Rio Grande do Sul / Hospital de Clínicas de Porto Alegre

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2013-04-30

Primary Completion

2014-08-31

Completion

2014-11-30

Countries

• Brazil

Study Locations