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Gluconeogenesis Rates and Its Precursors in Pediatric Sepsis

NCT01890928 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 19

Last updated 2016-04-28

No results posted yet for this study

Summary

Critically ill children have abnormal utilization of nutrients such as glucose, lipids and protein. Often sick children have increased glucose concentrations in blood. However, the origin of the high glucose has not been determined in these populations. There is a close interrelationship between protein and energy metabolism. An increase in the energy supply will not promote nitrogen retention unless the amino acid supply is adequate, and conversely, an increased amino acid supply will be useless if energy is limiting, hence the importance of adequate protein and energy intake. Our study aims to investigate the protein-energy interactions in critically ill septic children and adolescents with the objective to eventually provide the best nutritional support for these patients.

Conditions

Sponsors & Collaborators

  • University of Texas

    collaborator OTHER

  • The Cleveland Clinic

    lead OTHER

Principal Investigators

  • Leticia Castillo, MD · UT Southwestern Medical Center

Eligibility

Min Age
5 Years
Max Age
19 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2011-03-31
Primary Completion
2013-10-31
Completion
2013-10-31

Countries

  • United States

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01890928 on ClinicalTrials.gov