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Glucose Oxidase as Treatment Against Common Cold

NCT01883440 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 90

Last updated 2016-01-27

Study results available
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Summary

Glucose oxidase is a hydrogen peroxide producing enzyme, which also is present in honey. Human rhinoviruses are sensitive to the action of hydrogen peroxide, which is documented in laboratory studies.

In the present study we aim to investigate if a nasal spray with glucose oxidase could treat a common cold, when the treatment is started even after the onset of the symptoms. The study is randomized and placebo controlled.

Conditions

  • Common Cold

Interventions

DRUG

Glucose oxidase + glucose

Isotone saline + 200U/ml of glucose oxidase + 5% of glucose in a bag on valve nasal spray device

DRUG

Saline+glucose

Placebo arm

Sponsors & Collaborators

  • Krister Tano

    lead OTHER

Principal Investigators

  • Helena Toolanen, MD · Norrbottens Läns Landsting

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2013-01-31
Primary Completion
2013-08-31
Completion
2013-09-30

Countries

  • Sweden

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01883440 on ClinicalTrials.gov