MedTrace Logo

Impact of Catecholamine Spill-over on Outcome After RDN and EP Ablation

NCT01875809 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 80

Last updated 2013-06-12

No results posted yet for this study

Summary

Despite a rapidly increasing number of renal denervation (RDN) procedures, only little is known regarding the patient or procedural characteristics influencing the outcome. None of the detectable variables like number of ablation points, temperature rise, impedance drop, have been shown to correlate with the blood pressure (BP) reduction. In this study, the investigators assess different patient and procedural characteristics, like exact patient medication, stress hormones, heart rate variability, and focus on the change of the catecholamine spill-over, and the impact on BP and heart rate after RDN and after EP ablation. The investigators hypothesize the correlation between reduction of catecholamine spill-over due to denervation and the BP reduction. In this study, the investigators will assess 40 patients undergoing RDN and 40 patients undergoing EP ablation.

Conditions

Sponsors & Collaborators

  • University of Witten/Herdecke

    lead OTHER

Principal Investigators

  • Klaus A Tiroch, MD · University Wittn/Herdecke

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2013-03-31
Primary Completion
2015-02-28

Countries

  • Germany

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01875809 on ClinicalTrials.gov