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Surgical Treatment of Peri-implantitis

NCT01857804 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 100

Last updated 2014-11-13

No results posted yet for this study

Summary

The objective of this randomized controlled clinical trial is to evaluate the outcome of treatment of peri-implantitis with or without systemic antibiotics.

Specific aims are to analyze (i) the effect of systemic antibiotics and local antiseptics on the healing process, and (ii) the risk for recurrence of disease following surgical treatment of peri-implantitis.

Conditions

  • Peri-Implantitis

Interventions

DRUG

Amoxicillin

In the test group a systemic antibiotic regimen will be initiated at 3 days before surgery and continued for 10 days. (2 x 750mg amoxicillin/day or 2 x 1g amoxicillin/day depending on the weight of the patient)

DRUG

Chlorhexidine gluconate

The exposed implant surfaces will be cleaned 3 minutes with antiseptics (chlorhexidine gluconate 0,2%) during the surgical treatment

DRUG

Saline

The exposed implant surfaces will be cleaned 3 minutes with saline during the surgical treatment

Sponsors & Collaborators

  • The Swedish Research Council

    collaborator OTHER_GOV

  • Göteborg University

    lead OTHER

Principal Investigators

  • Tord Berglundh, Professor · Department of Periodontology, Institute of Odontology, The sahlgrenska academy, University of Gothenburg

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2013-01-31
Primary Completion
2014-11-30
Completion
2014-11-30

Countries

  • Sweden

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01857804 on ClinicalTrials.gov