Levels of the Stat4 Alpha and Stat4 Beta Isoforms in PBMCs From Patients With Crohn's Disease and Ulcerative Colitis
NCT00586599 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 51
Last updated 2015-04-03
Summary
The goal in these studies will be to assess the relative levels of the Stat4 alpha and Stat4 beta isoforms in PBMCs from patients with Crohn's Disease, ulcerative colitis, celiac disease or from control patients. We hypothesize that the beta to alpha ratio will be higher in patients with active disease and that there will be a correlation between the ratio and the severity of disease.
Conditions
Interventions
- OTHER
-
measurement of inflammatory markers
measuring inflammatory markers and comparing to controls.
Sponsors & Collaborators
-
Indiana University
lead OTHER
Principal Investigators
-
Steven J Steiner, MD · Indiana University
Study Design
- Allocation
- NON_RANDOMIZED
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 7 Years
- Max Age
- 17 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2007-08-31
- Primary Completion
- 2014-06-30
- Completion
- 2014-07-31
Countries
- United States
Study Locations
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