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Mucin Concentration in Sputum From COPD Patients During a Pulmonary Exacerbation

NCT01848093 · Status: WITHDRAWN · Type: OBSERVATIONAL

Last updated 2016-11-15

No results posted yet for this study

Summary

chronic obstructive pulmonary disease (COPD) is typically associated with mucus hypersecretion in the airways. In health, mucin is the major macromolecular component and is responsible for the protective and clearance properties of the mucus gel. In a recent study the investigators found that mucins are decreased and unstable in the sputum of adult cystic fibrosis (CF) patients.

In this study the investigators want to investigate the differences on the mucin quantity and quality of airway secretions during pulmonary exacerbation of patients with COPD.

Conditions

Interventions

OTHER

sputum collection

collecting of spontaneous sputum from the patient

Sponsors & Collaborators

  • Philipps University Marburg

    lead OTHER

Principal Investigators

  • Markus Henke, MD · University Marburg

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2008-12-31
Primary Completion
2013-06-30
Completion
2013-07-31

Countries

  • Germany

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01848093 on ClinicalTrials.gov