Study for Cognitive and Genetic Characterization of a 45-65 Years Old Population
NCT01835717 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 2743
Last updated 2021-06-10
Summary
Before Alzheimer's disease (AD) clinical symptoms appear, there is a long period when changes in the brain occur. In this long asymptomatic period or preclinical phase, studies with populations at risk of developing AD have shown cognitive differences compared to control groups without such risk. There is a need for short, sensitive, easily administered, reproducible, non-expensive and independent of socio-demographic influences tests enabling the detection of pre-symptomatic variations in memory, when the memory decline is still within a normal range.
Study main hypothesis: When evaluated with high-demanding tests of memory and executive function, the cognitive performance of cognitive healthy people aged between 45 and 65 and, extensively, to a group of up to 75 years, will vary significantly depending on clinical, socio-demographic and genetic features
Conditions
- Healthy Individuals
Sponsors & Collaborators
-
Obra Social La Caixa, Spain
collaborator UNKNOWN -
Barcelonabeta Brain Research Center, Pasqual Maragall Foundation
lead OTHER
Principal Investigators
-
José Luis Molinuevo, MD, PhD · Barcelonabeta Brain Research Center, Pasqual Maragall Foundation
Eligibility
- Min Age
- 45 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2013-04-30
- Primary Completion
- 2019-08-30
- Completion
- 2020-12-31
Countries
- Spain
Study Locations
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