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Effect of Isoflurane on Tissue Doppler Imaging of Mitral Annulus During Cardiac Surgery

NCT01819012 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 20

Last updated 2016-11-02

No results posted yet for this study

Summary

The purpose of this study is to determine Isoflurane's dose-dependent effect on left ventricular (LV) systolic function in cardiac surgery. The change of tissue Doppler imaging (TDI) of lateral mitral valve annular systolic velocity at three different isoflurane concentrations would be analyzed by using intraoperative transesophageal echocardiography (TEE) in cardiac surgery patients.

Conditions

  • Valvular Heart Disease
  • Ischemic Heart Disease

Interventions

DRUG

Isoflurane 1.0 MAC

10 min-inhalation of each concentration of isoflurane, 1.0 MAC

DRUG

Isoflurane 1.5 MAC

10 min-inhalation of each concentration of isoflurane, 1.5 MAC

DRUG

Isoflurane 2.0 MAC

10 min-inhalation of each concentration of isoflurane, 2.0 MAC

Sponsors & Collaborators

  • Konkuk University Medical Center

    lead OTHER

Principal Investigators

  • Tae-Yop Kim, MD, PhD · Konkuk University

Study Design

Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
20 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2013-03-31
Primary Completion
2013-11-30
Completion
2014-03-31

Countries

  • South Korea

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01819012 on ClinicalTrials.gov