The Effect of Simulated Obstructive Apnoea and Hypopnoea on Heart Rhythm in Patients With Paroxysmal Atrial Fibrillation

NCT01796080 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 45

Last updated 2013-12-23

No results posted yet for this study

Summary

In this randomised controlled cross-over study we will investigate whether intrathoracic pressure changes induced by simulated obstructive apnoea and hypopnoea trigger premature supraventricular and ventricular contractions as well as atrial fibrillation in patients with paroxysmal atrial fibrillation.

Conditions

  • Patients With Paroxysmal Atrial Fibrillation

Interventions

OTHER

Mueller manoeuvre

OTHER

Inspiratory threshold

OTHER

Expiratory apnoea

OTHER

Steady state normal breathing

Sponsors & Collaborators

  • University of Zurich

    lead OTHER

Principal Investigators

  • Malcolm Kohler, Prof MD · University Hospital Zurich, Division of Pneumology

Study Design

Allocation
RANDOMIZED
Purpose
DIAGNOSTIC
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2012-10-31
Primary Completion
2013-12-31
Completion
2013-12-31

Countries

  • Switzerland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01796080 on ClinicalTrials.gov