The Effect of Simulated Obstructive Apnoea and Hypopnoea on Heart Rhythm in Patients With Paroxysmal Atrial Fibrillation
NCT01796080 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 45
Last updated 2013-12-23
Summary
In this randomised controlled cross-over study we will investigate whether intrathoracic pressure changes induced by simulated obstructive apnoea and hypopnoea trigger premature supraventricular and ventricular contractions as well as atrial fibrillation in patients with paroxysmal atrial fibrillation.
Conditions
- Patients With Paroxysmal Atrial Fibrillation
Interventions
- OTHER
-
Mueller manoeuvre
- OTHER
-
Inspiratory threshold
- OTHER
-
Expiratory apnoea
- OTHER
-
Steady state normal breathing
Sponsors & Collaborators
-
University of Zurich
lead OTHER
Principal Investigators
-
Malcolm Kohler, Prof MD · University Hospital Zurich, Division of Pneumology
Study Design
- Allocation
- RANDOMIZED
- Purpose
- DIAGNOSTIC
- Masking
- DOUBLE
- Model
- CROSSOVER
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2012-10-31
- Primary Completion
- 2013-12-31
- Completion
- 2013-12-31
Countries
- Switzerland
Study Locations
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