Study of the Acute Effects of Triheptanoin in Heart Failure
NCT01787851 · Status: WITHDRAWN · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL
Last updated 2018-12-14
Summary
Patients with dilated cardiomyopathy who present for indwelling right heart catheterization will be enrolled and randomized to either control or triheptanoin oil for five days. Hemodynamics will be assess serially.
Conditions
- Congestive Heart Failure
- Non-ischemic Cardiomyopathy
Interventions
- DRUG
-
Triheptanoin oil
Sponsors & Collaborators
-
University of Texas Southwestern Medical Center
lead OTHER
Principal Investigators
-
Aslan T Turer, MD, MHS · UT-Southwestern
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- SINGLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2013-02-28
- Primary Completion
- 2014-02-28
- Completion
- 2014-02-28
Countries
- United States
Study Locations
More Related Trials
-
Therapy to Maintain Remission in Dilated Cardiomyopathy
NCT06091475 ·Status: RECRUITING ·Phase: NA
-
Ubiquinol Treatment in Patients With Heart Failure and Preserved Ejection Fraction
NCT02779634 ·Status: UNKNOWN ·Phase: PHASE2
-
Trimetazidine Therapy in Hypertrophic Cardiomyopathy
NCT01696370 ·Status: UNKNOWN ·Phase: PHASE2
-
Evaluate Efficacy, Safety and Tolerability of JTT-861 in Subjects With Heart Failure With Reduced Ejection Fraction
NCT06017609 ·Status: COMPLETED ·Phase: PHASE2
-
IC14 for Treatment of Acute Decompensated Heart Failure
NCT06556810 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1/PHASE2
-
A Study to Explore the Efficacy of TRV027 in Patients Hospitalized for Acute Decompensated Heart Failure
NCT01966601 ·Status: COMPLETED ·Phase: PHASE2
-
Effects of Triiodothyronine (T3) in Ischemic Heart Failure
NCT05384847 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1/PHASE2
-
Efficacy, Safety, and Tolerability of Perhexiline in Subjects With Hypertrophic Cardiomyopathy and Heart Failure
NCT02431221 ·Status: WITHDRAWN ·Phase: PHASE3
-
CoQ10 and D-ribose in Patients With Diastolic Heart Failure
NCT03133793 ·Status: COMPLETED ·Phase: PHASE2
-
Digoxin Withdrawal in Stable Heart Failure
NCT01398371 ·Status: COMPLETED ·Phase: NA
-
Efficacy and Safety of Ivabradine in Severe Congestive Heart Failure
NCT00202579 ·Status: COMPLETED ·Phase: PHASE2
-
Tezosentan in Acute Heart Failure
NCT00525707 ·Status: COMPLETED ·Phase: PHASE3
-
Interleukin-1 Blockade in Acute Myocardial Infarction to Prevent Heart Failure
NCT05177822 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
The Effect of Trimetazidine on Mitochondrial Function, Myocardial Performance, and Invasive Hemodynamics in Patients Diagnosed With Wild-Type Transthyretin Cardiac Amyloidosis
NCT05633563 ·Status: COMPLETED ·Phase: PHASE4
-
Study to Assess the Safety and Tolerability of IV Tonapofylline in Subjects With Acute Decompensated Heart Failure (ADHF) and Renal Insufficiency
NCT00709865 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of Ularitide in the Treatment of Subjects With Acute Decompensated Heart Failure
NCT00487799 ·Status: WITHDRAWN ·Phase: PHASE1
-
A Study to Investigate the Safety, Tolerability, Pharmacodynamics and Pharmacokinetics of an Intravenous Solution of JNJ-39588146 or Placebo in Patients With Heart Failure
NCT01120210 ·Status: COMPLETED ·Phase: PHASE2
-
Exogenous Ketones for Acutely Decompensated HEart Failure
NCT04698005 ·Status: UNKNOWN ·Phase: PHASE3
-
N-3 Fatty Acids for the Prevention of Atrial Fibrillation in Patients With Acute Heart Failure
NCT00692718 ·Status: UNKNOWN ·Phase: PHASE4
-
Double Blind Randomized Placebo Controlled Trial of Natrecor in Acute Decompensated Heart Failure With Normal EF
NCT00505791 ·Status: WITHDRAWN ·Phase: PHASE4
-
Withdrawal of Pharmacological Treatment in Patients Responding to Cardiac Resynchronization Therapy:
NCT05151861 ·Status: UNKNOWN ·Phase: PHASE4
-
Safety and Efficacy Study of Once and Twice Daily Doses of MCC-135 in Subjects With Congestive Heart Failure.
NCT00050076 ·Status: COMPLETED ·Phase: PHASE2
-
Study of DITPA in Patients With Congestive Heart Failure
NCT00103519 ·Status: TERMINATED ·Phase: PHASE2
-
Haemodynamic Effects of Dobutamine in Patients With Wild-type Transthyretin Amyloid Cardiomyopathy (ATTRwt)
NCT06318260 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Desflurane-induced Myocardial Protection
NCT02019797 ·Status: UNKNOWN ·Phase: PHASE4