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Bronchial Colonization With Fungi and Late Respiratory Acquired Pneumonia

NCT01770015 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 213

Last updated 2022-11-04

No results posted yet for this study

Summary

Ventilator acquired pneumonia (VAP) are severe nosocomial infections. On the other side, bronchial fungi colonization is commonly observed in ICU; therefore, the investigators propose to study the role of bronchial fungi colonization on the occurrence of VAP taking into account the immune status of the patient and the antibiotic and antifungal treatments he has received.

Conditions

  • Ventilator Acquired Pneumonia

Interventions

PROCEDURE

biological sampling

cutaneous, rectal, nose and mouth swabs to identify potential fungi colonization

PROCEDURE

sampling blood

HLA DR antigen, cytokines (IL 6 and 10), B-glucan

PROCEDURE

endotracheal aspiration

fungi and bacteria endotracheal aspiration

Sponsors & Collaborators

  • University Hospital, Grenoble

    lead OTHER

Principal Investigators

  • TIMSIT Jean-François, PU/PH · University Hospital, Grenoble

Study Design

Allocation
NA
Purpose
DIAGNOSTIC
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2011-11-30
Primary Completion
2016-03-31
Completion
2016-09-30

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01770015 on ClinicalTrials.gov