Build Better Bones With Exercise

Summary

The long-term goal of our research team is to conduct a large multicentre study to evaluate whether tailored home exercise can prevent fractures in high-risk individuals. The proposed project will address the feasibility of such a trial, but will also evaluate the effect of exercise on quality of life, posture and many other outcomes important to individuals with vertebral fractures. Physiotherapists will conduct 6 home visits with participants to deliver the intervention (or social visit for controls) using a similar model to previous work by our team and others. The purpose of this pilot study is determining the feasibility of recruitment, retention and adherence of an international multicentre randomized controlled study evaluating the efficacy of thrice-weekly home exercise for one year among women with vertebral fracture. As secondary objectives, the investigators will examine the effects of exercise on function, balance, quality of life, pain, falls and fractures. The primary hypothesis is that the investigators will successfully recruit and retain the target sample, and achieve an adherence rate of 60%.

Conditions

• Osteoporotic Fractures
• Spinal Fractures

Interventions

BEHAVIORAL

Exercise and behaviour change strategies

1. cardiovascular exercise (e.g., marching, walking) for ≥10 minutes per day 2. postural retraining and balance exercises ≥3 days a week (will be encouraged to do these daily) 3. perform muscle strengthening and balance training exercises ≥ 3 days a week 4. the exercise intervention was developed using the Bone Fit program as a framework (http://www.bonefit.ca/). The physical therapist will tailor exercises and work with participant to integrate them into their day.

Sponsors & Collaborators

• Canadian Institutes of Health Research (CIHR)

  collaborator OTHER_GOV

• University of Western Ontario, Canada

  collaborator OTHER

• University Health Network, Toronto

  collaborator OTHER

• McMaster University

  collaborator OTHER

• University of Melbourne

  collaborator OTHER

• University of British Columbia

  collaborator OTHER

• University of Waterloo

  lead OTHER

Principal Investigators

• Lora Giangregorio, PhD · University of Waterloo

Study Design

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

SINGLE

Model

PARALLEL

Eligibility

Min Age

65 Years

Sex

FEMALE

Healthy Volunteers

No

Timeline & Regulatory

Start

2013-01-31

Primary Completion

2016-12-31

Completion

2016-12-31

Countries

• Canada

Study Locations