A Study of the Safety and Efficacy of Anacetrapib (MK-0859) When Added to Ongoing Statin Therapy in Japanese Participants With Dyslipidemia (MK-0859-051 AM1)
NCT01760460 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 307
Last updated 2017-06-01
Summary
This study will evaluate the effects of anacetrapib (MK-0859) on low-density lipoprotein-cholesterol (LDL-C) when compared to placebo in Japanese participants with dyslipidemia when added to an existing statin-modifying therapy.
Conditions
Interventions
- DRUG
-
Anacetrapib
- DRUG
-
Placebo for anacetrapib
Sponsors & Collaborators
- lead INDUSTRY
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2013-03-14
- Primary Completion
- 2015-03-04
- Completion
- 2015-03-04
More Related Trials
-
A Dose-Finding Study in Japanese Patients to Evaluate the Effect of Obicetrapib as an Adjunct to Stable Statin Therapy.
NCT05421078 ·Status: COMPLETED ·Phase: PHASE2
-
The Effect of MK0859 on Lipoprotein Metabolism in Patients With Dyslipidemia (0859-026 AM3)
NCT00990808 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Assess the Tolerability and Efficacy of Anacetrapib in Patients With Coronary Heart Disease (CHD) or CHD Risk-Equivalent Disease (MK-0859-019)
NCT00685776 ·Status: COMPLETED ·Phase: PHASE3
-
Efficacy and Tolerability of Anacetrapib Added to Ongoing Lipid-Lowering Therapy in Adult Participants With Homozygous Familial Hypercholesterolemia (HoFH) (MK-0859-042)
NCT01841684 ·Status: TERMINATED ·Phase: PHASE3
-
Randomized Study of Obicetrapib as an Adjunct to Statin Therapy
NCT04753606 ·Status: COMPLETED ·Phase: PHASE2
-
A Clinical Trial to Assess the Long Term Safety and Tolerability of MK-0653C in Japanese Participants With Hypercholesterolemia (MK-0653C-384)
NCT02460159 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of Evacetrapib (LY2484595) in Combination With Atorvastatin in Japanese Participants With Primary Hypercholesterolemia
NCT02260648 ·Status: TERMINATED ·Phase: PHASE3
-
A Phase III Confirmatory Study of K-877 (Pemafibrate) in Patients With Hypercholesterolemia and Statin Intolerance
NCT05923281 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of LY2484595 in Japanese Subjects
NCT01375075 ·Status: COMPLETED ·Phase: PHASE2
-
A Confirmatory Trial of ETC-1002 in Patients With Hyper-LDL Cholesterolemia
NCT05683340 ·Status: COMPLETED ·Phase: PHASE3
-
Efficacy and Safety Evaluation of Alirocumab in Patients With Heterozygous Familial Hypercholesterolemia or High Cardiovascular Risk Patients With Hypercholesterolemia on Lipid Modifying Therapy (ODYSSEY JAPAN)
NCT02107898 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of Evacetrapib (LY2484595) in Japanese Participants With Primary Hypercholesterolemia
NCT02260635 ·Status: TERMINATED ·Phase: PHASE3
-
Evaluation of Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of TA-8995 After Multiple Doses in Healthy Subjects
NCT01879020 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of MK0859 in Patients With Primary Hypercholesterolemia or Mixed Hyperlipidemia (MK-0859-011)(COMPLETED)
NCT00565292 ·Status: COMPLETED ·Phase: PHASE1
-
Efficacy and Safety of Alirocumab in Patients With Hypercholesterolemia Not Adequately Controlled With Non-statin Lipid Modifying Therapy or the Lowest Strength of Statin
NCT02584504 ·Status: COMPLETED ·Phase: PHASE3
-
Safety and Efficacy Study of JTT-705 in Combination With Atorvastatin 20 mg in Patients With Low High-Density Lipoprotein (HDL) Levels
NCT00689442 ·Status: COMPLETED ·Phase: PHASE2
-
Evaluate Safety and Efficacy of ABT-335 in Combination With Atorvastatin in Subjects With Multiple Abnormal Lipid Levels in the Blood
NCT00300469 ·Status: COMPLETED ·Phase: PHASE3
-
MK0859 Dose-Ranging Study (0859-003)
NCT00325455 ·Status: TERMINATED ·Phase: PHASE2
-
Dose Ranging Study Of Bococizumab (PF-04950615; RN316) In Hypercholesterolemic Japanese Subjects
NCT02055976 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy and Safety of Extended Release (ER) Niacin/Laropiprant When Added to Ongoing Lipid-Modifying Therapy in Patients With High Cholesterol or Abnormal Lipid Levels (MK-0524A-133)
NCT01274559 ·Status: TERMINATED ·Phase: PHASE3
-
Safety and Efficacy of Lapaquistat Acetate Taken Alone and With Atorvastatin in Subjects With Primary Dyslipidemia
NCT00487994 ·Status: COMPLETED ·Phase: PHASE3
-
Efficacy and Safety of JTT-705 300, 600 And 900mg in Comparison With Placebo in Patients With Type II Hyperlipidaemia
NCT00686010 ·Status: COMPLETED ·Phase: PHASE2
-
Safety and Efficacy Study of JTT-705 in Combination With Simvastatin 40 mg in Patients With Low High-Density Lipoprotein (HDL) Levels
NCT00688558 ·Status: COMPLETED ·Phase: PHASE2
-
A Multicenter Study Comparing the Safety and Efficacy of ABT-335 and Rosuvastatin Calcium Combination Therapy to Monotherapy in Subjects With Dyslipidemia
NCT00463606 ·Status: COMPLETED ·Phase: PHASE3
-
Evaluation of Alirocumab in Addition to Lipid-Modifying Therapy in Patients With High Cardiovascular Risk and Hypercholesterolemia in South Korea and Taiwan
NCT02289963 ·Status: COMPLETED ·Phase: PHASE3