Efficacy of Acarbose on Intestinal Microbiome and Incretins of Type 2 Diabetes
NCT01758471 · Status: UNKNOWN · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 160
Last updated 2013-01-01
Summary
This study is aimed to investigate the effect of acarbose on intestinal microbiome and incretins, therefore to explore the new pathways or new targets to treat type 2 diabetes.
Conditions
Interventions
- DRUG
-
Glipizide
glipizide 5mg per pill 5mg tid p.o. for 3 month
- DRUG
-
Acarbose
Acarbose 50mg per pill 100mg to 150mgtid p.o.(oral) for 3 month
Sponsors & Collaborators
-
Shanghai Jiao Tong University School of Medicine
lead OTHER
Principal Investigators
-
Guang Ning, M.D. Ph.D. · Shanghai Jiao Tong University School of Medicine
Study Design
- Allocation
- RANDOMIZED
- Purpose
- BASIC_SCIENCE
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 40 Years
- Max Age
- 60 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2012-12-31
- Primary Completion
- 2013-12-31
- Completion
- 2014-06-30
Countries
- China
Study Locations
More Related Trials
-
Study of Metformin and S. Baicalensis Combination Therapy in Type 2 Diabetes Mellitus Patients
NCT02844803 ·Status: UNKNOWN ·Phase: EARLY_PHASE1
-
A Multicenter, Randomized, Open-Label, Parallel-Controlled Clinical Study Comparing the Efficacy and Safety of Cofrogliptin Versus Acarbose in Drug-Naïve Patients With Type 2 Diabetes
NCT07122102 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Efficacy and Safety of the Met+SGLT-2i+GLP-1RA in Patients With Type 2 Diabetes With Poor Glycemic Control
NCT07244003 ·Status: RECRUITING ·Phase: PHASE4
-
Efficacy and Safety of SHR-3167 and Insulin Glargine in Type 2 Diabetes Subjects
NCT06688123 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
24-Week, Multicenter, Randomized, Parallel-group, Open-label, Active Controlled Phase IV Study to Assess the Efficacy, Safety and Tolerability of Saxagliptin Compared With Acarbose When in Combination With Metformin in Patients With T2D Inadequately Controlled With Metformin Monotherapy
NCT02243176 ·Status: COMPLETED ·Phase: PHASE4
-
A Study to Evaluate the Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of PF-06882961 in Chinese Adults With Type 2 Diabetes Mellitus
NCT04889157 ·Status: COMPLETED ·Phase: PHASE1
-
Therapies on Newly Diagnosed Type 2 Diabetes Patients With High Glucose Toxicity Which Protect Islet β Cell
NCT03180281 ·Status: UNKNOWN ·Phase: NA
-
Effect of Akkermansia Muciniphila WST01 Strain in Overweight or Obese Patients With Type 2 Diabetes
NCT04797442 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Safety and Efficacy of S-707106 in Subjects With Type 2 Diabetes Mellitus and Inadequate Glycemic Control With Metformin Therapy
NCT01240759 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of the Glucodynamic Effects of Dulaglutide (LY2189265) in Japanese Participants With Type 2 Diabetes
NCT03315780 ·Status: COMPLETED ·Phase: PHASE4
-
A Study for Sufficient Acarbose Decreased Glucose Excursion in Type 2 Diabetic Patients
NCT03805191 ·Status: UNKNOWN
-
Study of AC-201 in Patients With Type 2 Diabetes Mellitus
NCT01276106 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of Dulaglutide in Japanese Participants With Type 2 Diabetes
NCT02750410 ·Status: COMPLETED ·Phase: PHASE4
-
Effects of Acarbose Versus Glibenclamide on MAGE and Oxidative Stress in Patients With Type 2 DM
NCT00417729 ·Status: COMPLETED ·Phase: PHASE4
-
Efficacy and Safety of SHR3824 as Monotherapy in Subjects With Type 2 Diabetes
NCT03159052 ·Status: UNKNOWN ·Phase: PHASE3
-
A Study of Dulaglutide (LY2189265) in Chinese Participants With Type 2 Diabetes
NCT04591626 ·Status: COMPLETED ·Phase: PHASE3
-
Meta-analysis in Post-marketing Surveillances for SGLT2 Inhibitors in Patients With Type 2 Diabetes Mellitus
NCT02284269 ·Status: UNKNOWN
-
Japan Early Diabetes Intervention Study
NCT00464594 ·Status: UNKNOWN ·Phase: NA
-
A Study of BGM0504 in Chinese Patients With Type 2 Diabetes
NCT06974825 ·Status: COMPLETED ·Phase: PHASE2
-
Special Drug Use Investigation of Glucobay OD
NCT01685502 ·Status: COMPLETED
-
Study on the Prognosis and Effect of Anti-diabetic Drugs on Type-2 Diabetes Mellitus With Coronary Artery Disease
NCT00513630 ·Status: COMPLETED ·Phase: PHASE4
-
Multiple Ascending Doses of Globalagliatin Hydrochloride in Type 2 Diabetes Mellitus
NCT03414892 ·Status: COMPLETED ·Phase: PHASE1
-
A Study Evaluating the Safety, Tolerability, and Pharmacodynamic Effects of GLY-200 in Type 2 Diabetic Patients
NCT05478525 ·Status: COMPLETED ·Phase: PHASE2
-
MK-0941 Multiple Dose Study in Japanese Patients With Type 2 Diabetes (MK-0941-011).
NCT00754130 ·Status: COMPLETED ·Phase: PHASE1
-
Dose Ranging Study of Albiglutide in Japanese Subjects
NCT01098461 ·Status: COMPLETED ·Phase: PHASE2