Study of Two Surgical Drilling Techniques to Treat Juvenile Osteochondritis Dissecans of the Knee

Summary

The purpose of this study is to compare the functional, clinical and radiographic outcomes associated with trans-articular drilling versus retro-articular drilling, two commonly employed techniques of operative treatment for stable forms of juvenile osteochondritis dissecans (JOCD) lesions. This study also aims to better define the natural history of this condition in its most commonly identified pathological state (as a stable lesion) following surgical intervention by determining the rate of radiographic healing and any need for secondary surgery.

Conditions

• Juvenile Osteochondritis Dissecans

Interventions

PROCEDURE

Retro-articular drilling

* Drilling must be performed under AP and lateral fluoroscopic guidance, with no additional drilling in 'trans-articular', or intra-articular trans-condylar fashion. * Use a 0.045 K-wire for drilling. * Minimum of 8 wire passes per square centimeter with no maximum number of wire passes.

PROCEDURE

Trans-articular drilling

* Drilling must be performed, under arthroscopic visualization, directly through the articular cartilage, with no additional drilling in 'retro-articular', 'extra-articular', or trans-condylar (through the intercondylar notch) * Use a 0.045 K-wire for drilling * A minimum 4 wire passes per square centimeter, with a maximum of 5 wire passes per square centimeter

Sponsors & Collaborators

• Pediatric Orthopaedic Society of North America

  collaborator OTHER

• University of Pennsylvania

  collaborator OTHER

• Tennessee Orthopedic Alliance

  collaborator OTHER

• Children's Hospital Medical Center, Cincinnati

  collaborator OTHER

• Children's Hospital and Health System Foundation, Wisconsin

  collaborator OTHER

• Washington University School of Medicine

  collaborator OTHER

• The Hospital for Sick Children

  collaborator OTHER

• Children's Hospital of Philadelphia

  collaborator OTHER

• Kaiser Permanente

  collaborator OTHER

• Rady Children's Hospital, San Diego

  collaborator OTHER

• St. Luke's Children's Hospital

  collaborator OTHER

• Medical College of Wisconsin

  collaborator OTHER

• Connecticut Children's Medical Center

  collaborator OTHER

• Hospital for Special Surgery, New York

  collaborator OTHER

• Boston Children's Hospital

  lead OTHER

Principal Investigators

• Benton Heyworth, M.D. · Boston Children's Hospital

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Model

PARALLEL

Eligibility

Min Age

8 Years

Max Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2013-01-18

Primary Completion

2019-07-29

Completion

2020-10-16

Countries

• United States
• Canada

Study Locations