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Genetic and Neural Predictors of Adolescent Depression

NCT01743716 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 100

Last updated 2026-03-12

No results posted yet for this study

Summary

This study aims to examine the relationship between mood and brain activity in adolescent girls in order to better understand the genetic and neural predictors of adolescent depression. The participants in this study will be healthy female adolescents aged 12-14 and their mothers. They will participate for a total of six months. Adolescent participants will have three study sessions at McLean Hospital, and during two of them, their mothers will also have assessments. Adolescent assessments will include interviews, questionnaires, computer tasks, and collection of a saliva sample for genetic analyses. Their second study visit will include an fMRI scan. Parent assessments will include an interview, questionnaires, and a computer task.

Conditions

Sponsors & Collaborators

  • The Klingenstein Third Generation Foundation

    collaborator OTHER

  • The Dana Foundation

    collaborator OTHER

  • Mclean Hospital

    lead OTHER

Principal Investigators

  • Randy P. Auerbach, PhD · Mclean Hospital

  • Diego A. Pizzagalli, PhD · Mclean Hospital

Eligibility

Min Age
12 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2013-04-30
Primary Completion
2021-12-31
Completion
2021-12-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01743716 on ClinicalTrials.gov