Cabergoline in Metastatic Breast Cancer
NCT01730729 · Status: COMPLETED · Phase: EARLY_PHASE1 · Type: INTERVENTIONAL · Enrollment: 20
Last updated 2019-09-17
Summary
Prolactin is a hormone produced in the pituitary gland. Previous studies have revealed that elevated levels of the hormone prolactin might be associated with an increased risk of breast cancer. Cabergoline has been shown to lower prolactin levels in the blood.
The purpose of this study is to evaluate the effectiveness of cabergoline in treating metastatic breast cancer disease in those who test positive for the prolactin receptor.
Conditions
- Recurrent Breast Cancer
- Stage IV Breast Cancer
Interventions
- DRUG
-
cabergoline
Given orally
Sponsors & Collaborators
-
Lynn Sage Foundation
collaborator UNKNOWN - lead OTHER
Principal Investigators
-
Virginia Kaklamani · Northwestern University
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2013-02-11
- Primary Completion
- 2015-12-15
- Completion
- 2017-10-27
Countries
- United States
Study Locations
More Related Trials
-
Paclitaxel With or Without Carboplatin in Treating Women With Metastatic Breast Cancer
NCT00025688 ·Status: UNKNOWN ·Phase: PHASE3
-
Lapatinib in Treating Brain Metastases in Patients With Stage IV Breast Cancer and Brain Metastases
NCT00098605 ·Status: COMPLETED ·Phase: PHASE2
-
Docetaxel and Carboplatin in Treating Women With Metastatic Breast Cancer
NCT00005963 ·Status: COMPLETED ·Phase: PHASE2
-
PTC299 and Hormonal Agent for Treatment of Metastatic Breast Cancer
NCT00508586 ·Status: COMPLETED ·Phase: PHASE1
-
Carboplatin and Bevacizumab for Progressive Breast Cancer Brain Metastases
NCT01004172 ·Status: COMPLETED ·Phase: PHASE2
-
Study of Cabazitaxel in Patients With Metastatic Breast Cancer Previously Treated With Taxanes
NCT01693549 ·Status: COMPLETED ·Phase: PHASE2
-
A Phase 2 Study of PCS6422 With Capecitabine in Patients With Advanced or Metastatic Breast Cancer
NCT06568692 ·Status: RECRUITING ·Phase: PHASE2
-
Bevacizumab With Etoposide and Cisplatin in Breast Cancer Patients With Brain and/or Leptomeningeal Metastasis
NCT01281696 ·Status: COMPLETED ·Phase: PHASE2
-
Carboplatin and Eribulin Mesylate in Triple Negative Breast Cancer Patients
NCT01372579 ·Status: UNKNOWN ·Phase: PHASE2
-
Chemotherapeutic Agents in Brain/Breast
NCT00795678 ·Status: COMPLETED
-
Testing Sacituzumab Govitecan Therapy in Patients With HER2-Negative Breast Cancer and Brain Metastases
NCT04647916 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Liposomal Cytarabine and High-Dose Methotrexate in Treating Patients With Central Nervous System Metastases From Breast Cancer
NCT00992602 ·Status: COMPLETED ·Phase: PHASE2
-
Safety and Efficacy Study of a New Chemotherapy Agent to Treat Metastatic Breast Cancer
NCT00288249 ·Status: COMPLETED ·Phase: PHASE2
-
Capecitabine and Pegylated Interferon Alfa-2a in Treating Patients With Recurrent or Progressive Brain Metastases Due to Breast Cancer
NCT00227656 ·Status: TERMINATED ·Phase: PHASE2
-
Trotabresib in Combination With Vinorelbine and Radiation Therapy for the Treatment of HER2+ Breast Cancer With Central Nervous System or Leptomeningeal Metastasis
NCT06137651 ·Status: WITHDRAWN ·Phase: PHASE1
-
Determine Feasibility of Quantifying Apoptosis and Bcl-2 Expression in CTCs in Women With Metastatic Breast Cancer
NCT00156273 ·Status: COMPLETED
-
Pyrazoloacridine in Treating Women With Metastatic Breast Cancer
NCT00002585 ·Status: COMPLETED ·Phase: PHASE2
-
Paclitaxel and Capecitabine in Treating Women With Metastatic Breast Cancer
NCT00005649 ·Status: COMPLETED ·Phase: PHASE2
-
ZK219477 (Sagopilone) in Patients With Breast Cancer and Brain Metastases
NCT00496379 ·Status: TERMINATED ·Phase: PHASE2
-
Study of Biweekly Capecitabine Dosing With Bevacizumab for the Treatment of Metastatic Breast Cancer Based Upon the Norton-Simon Mathematical Model
NCT00468585 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Capecitabine in Treating Patients With Metastatic Breast Cancer
NCT00274768 ·Status: COMPLETED ·Phase: PHASE2
-
Capecitabine and Lapatinib Ditosylate With or Without Cixutumumab in Treating Patients With Previously Treated HER2-Positive Stage IIIB-IV Breast Cancer
NCT00684983 ·Status: COMPLETED ·Phase: PHASE2
-
Cabazitaxel Plus Lapatinib as Therapy for HER2-Positive Metastatic Breast Cancer Patients With Intracranial Metastases
NCT01934894 ·Status: TERMINATED ·Phase: PHASE2
-
Capecitabine in Treating Women With Advanced or Metastatic Breast Cancer
NCT00026442 ·Status: UNKNOWN ·Phase: PHASE2
-
Neoadjuvant Platinum-based Chemoradiation Therapy for Locally Advanced Triple Negative Breast Cancer
NCT01167192 ·Status: TERMINATED ·Phase: PHASE2