A Study of E7080 in Subjects With Advanced Thyroid Cancer
NCT01728623 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 51
Last updated 2020-08-14
Summary
This study is to evaluate the safety, efficacy, and pharmacokinetics of E7080 when orally administered once daily (QD) in subjects with advanced thyroid cancer.
Conditions
Interventions
- DRUG
-
E7080 capsule
E7080 is administered as continuous once daily dosing in an uncontrolled manner
Sponsors & Collaborators
-
Eisai Co., Ltd.
lead INDUSTRY
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 20 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2012-09-03
- Primary Completion
- 2015-07-09
- Completion
- 2015-10-01
Countries
- Japan
Study Locations
More Related Trials
-
Study of Anlotinib Hydrochloride Capsules in the Treatment of Locally Advanced or Metastatic Radioiodine-Refractory Differentiated Thyroid Carcinoma
NCT05994365 ·Status: RECRUITING
-
Recombinant Human Thyroid Stimulating Hormone for Radioiodine 131I Treatment
NCT06405217 ·Status: RECRUITING ·Phase: NA
-
Clinical Trial of Dose-tolerance, Pharmacokinetics and Iodine Uptake For rhTSH In Post-thyroidectomized Patients
NCT04137185 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Study of the Anti-angiogenesis Agent AG-013736 in Patients With Metastatic Thyroid Cancer
NCT00094055 ·Status: COMPLETED ·Phase: PHASE2
-
Thyroxine Replacement Therapy After Lobectomy for Low-risk Papillary Thyroid Carcinoma
NCT06087068 ·Status: RECRUITING ·Phase: PHASE2
-
A Trial of Lenvatinib (E7080) in Subjects With Iodine-131 Refractory Differentiated Thyroid Cancer to Evaluate Whether an Oral Starting Dose of 18 Milligram (mg) Daily Will Provide Comparable Efficacy to a 24 mg Starting Dose, But Have a Better Safety Profile
NCT02702388 ·Status: COMPLETED ·Phase: PHASE2
-
CUDC-907 Treatment in People With Metastatic and Locally Advanced Thyroid Cancer
NCT03002623 ·Status: TERMINATED ·Phase: PHASE2
-
HRQOL in Locally Advanced Thyroid Carcinoma
NCT05824312 ·Status: RECRUITING
-
Differentiated Thyroid Cancer Patients Treated With Different Doses of Radioactive Iodine.
NCT06134830 ·Status: NOT_YET_RECRUITING
-
The Safety and Effectiveness of rhTSH in Radioiodine Treatment for Patients With Differentiated Thyroid Cancer.
NCT04447183 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Treatment for Patients With Metastatic Thyroid Cancer
NCT00176748 ·Status: COMPLETED ·Phase: PHASE2
-
Impact of Conventional Treatments and Clinical Variables on Thyroid Cancer
NCT05752604 ·Status: RECRUITING
-
Efficacy and Tolerability of ZD6474 in Patients With Thyroid Cancer
NCT00098345 ·Status: COMPLETED ·Phase: PHASE2
-
Comparison of the Safety and Successful Ablation of Thyroid Remnant in Post-thyroidectomized Euthyroid Patients (i.e. Patients Administered Thyrogen) Versus Hypothyroid Patients (no Thyrogen) Following 131I Administration
NCT00196729 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of Sustained-Release Liothyronine Sodium (T3) in Healthy Subjects
NCT01581463 ·Status: COMPLETED ·Phase: PHASE1
-
Anlotinib or Penpulimab in Combination With RAI for DTC
NCT04952493 ·Status: UNKNOWN ·Phase: PHASE2
-
A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Trial of Lenvatinib (E7080) in 131I-Refractory Differentiated Thyroid Cancer (DTC)
NCT01321554 ·Status: COMPLETED ·Phase: PHASE3
-
A Retrospective Observational Study Comparing Two Different Treatment Options in Thyroid Cancer Patients With T4 Tumours
NCT01736163 ·Status: COMPLETED
-
Method of Endogenous TSH Stimulation in the Follow-up of Differentiated Thyroid Cancer
NCT01840332 ·Status: COMPLETED ·Phase: NA
-
Sorafenib as Adjuvant to Radioiodine Therapy in Non-Medullary Thyroid Carcinoma
NCT00887107 ·Status: COMPLETED ·Phase: PHASE2
-
Thyroid Hormone Replacement After Radio Iodine: Value and Efficacy
NCT06647602 ·Status: NOT_YET_RECRUITING
-
Safety and Efficacy of VB-111 in Subjects With Advanced Differentiated Thyroid Cancer
NCT01229865 ·Status: COMPLETED ·Phase: PHASE2
-
Urinary Exosomal Biomarkers of Thyroglobulin and Galectin-3 for Prognosis and Follow-up in Patients of Thyroid Cancer
NCT04948437 ·Status: ACTIVE_NOT_RECRUITING
-
Systematic Radioiodine Administration Versus Decision of Radioiodine Treatment Guided by a Post-operative Work-up
NCT04290663 ·Status: RECRUITING ·Phase: PHASE3
-
Study of Resistance to Thyroid Hormone After Long-term Exposure in People With Thyroid Cancer
NCT04868045 ·Status: WITHDRAWN ·Phase: PHASE1