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Cell Therapy in Severe Chronic Ischemic Heart Disease

NCT01727063 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 143

Last updated 2019-08-30

No results posted yet for this study

Summary

Patients with advanced coronary artery disease usually undergo incomplete myocardial revascularization due to the extension and diffuseness of the disease, with very poor distal arterial beds unsuitable for direct revascularization.

This study was designed to test the hypothesis that direct, intramyocardial injection of autologous bone marrow cells may further improve myocardial perfusion in patients undergoing incomplete bypass surgery.

Conditions

Interventions

PROCEDURE

Cell Therapy

Intramyocardial injection of autologous bone marrow-derived cells

Sponsors & Collaborators

  • Ministry of Health, Brazil

    lead OTHER_GOV

Principal Investigators

  • Jose Eduardo Krieger, MD, PhD · Heart Institute

  • Carlos Eduardo Rochitte, MD, PhD · Heart Institute

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2006-01-31
Primary Completion
2018-07-31
Completion
2018-07-31

Countries

  • Brazil

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01727063 on ClinicalTrials.gov