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The Relationship Between Serum Levels of Angiogenin, bFGF, VEGF and Ocular Involvement in Patients With Behçet's Disease

NCT01720628 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 86

Last updated 2012-11-02

No results posted yet for this study

Summary

Objectives: Behçet's disease (BD) is a systemic vasculitis. Since vascular endothelial dysfunction plays a prominent role in the pathogenesis of the disease, we considered angiogenic cytokines as an interesting target for investigation in BD. The aim of this study was to investigate the possible role of angiogenin, vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF) in the pathogenesis of BD.

Design and Methods: Sixty five patients with BD and 21 healthy control subjects were included in the study. Serum angiogenin, bFGF and VEGF concentrations were determined by using in vitro enzyme immunoassay (ELISA) kits according to the manufacturer's instructions.

Conditions

  • Behçet's Disease

Interventions

OTHER

serum levels of angiogenin, bFGF, VEGF

Behçet's patients

Sponsors & Collaborators

  • Turkish Ophthalmology Society

    lead OTHER

Principal Investigators

  • ali yalçındağ · * Dışkapı Yıldırım Beyazıt Training and Research Hospital, Department of Clinical Biochemistry

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2011-11-30
Primary Completion
2011-11-30
Completion
2012-02-29

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01720628 on ClinicalTrials.gov