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Effect of Intraperitoneal and Intravenous Lignocaine on Pain Relief Following Laparoscopic Cholecystectomy

NCT01717222 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 50

Last updated 2012-10-30

No results posted yet for this study

Summary

Laparoscopic Cholecystectomy is the treatment of choice for patients with symptomatic gall stones. For pain relief following laparoscopic cholecystectomy both intraperitoneal and intravenous administration of lignocaine has been used. But it is not clear from the existing literature which form of administration is more effective for pain relief. Hence this study has been undertaken with the following hypothesis : Intravenous lignocaine is superior to intraperitoneal lignocaine for postoperative pain relief and minimizing the stress response in laparoscopic cholecystectomy.

Conditions

  • Pain, Postoperative
  • Analgesic Requirement
  • Stress Response
  • Return of Bowel Activity
  • Inadequate or Impaired Respiratory Function

Interventions

DRUG

Intraperitoneal Lignocaine

Patients will receive 100 ml of 0.2% lignocaine

DRUG

Intravenous Lignocaine

Intravenous group patients will receive 1.5mg/kg of lignocaine as bolus dose at induction and 2mg/kg/hour as continuous infusion until one hour after surgery

Sponsors & Collaborators

  • Jawaharlal Institute of Postgraduate Medical Education & Research

    lead OTHER_GOV

Principal Investigators

  • Dr. Sarath Chandra Sistla, M.S., · Jawaharlal Institute of Postgraduate Medical Education & Research

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
20 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2011-12-31
Primary Completion
2012-10-31
Completion
2012-10-31

Countries

  • India

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01717222 on ClinicalTrials.gov