Neurofibromatosis Type 1 Brain Tumor Genetic Risk
NCT01707836 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 176
Last updated 2017-05-09
Summary
This study will analyze DNA samples to determine associations between maternal and offspring genetic factors and pediatric brain tumor development in children with Neurofibromatosis Type 1. Participating families (mother, father, child) will be asked to complete a short questionnaire and provide DNA samples (either saliva or blood). The information gained from your participation may one day help doctors develop strategies to reduce brain tumor risk in individuals with NF1. Please note: there is no therapy associated with this study.
Conditions
- Neurofibromatosis Type 1
- Pediatric Brain Tumor
Sponsors & Collaborators
-
Washington University School of Medicine
lead OTHER
Principal Investigators
-
Kimberly J Johnson, PhD · Washington University School of Medicine
Eligibility
- Max Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2012-10-31
- Primary Completion
- 2017-05-08
- Completion
- 2017-05-08
Countries
- United States
Study Locations
More Related Trials
-
Genomics, Single Nucleotide Polymorphisms (SNPs), and Clinical Neonatology
NCT00315263 ·Status: COMPLETED
-
Evaluating Genetic Modifiers of Cutaneous Neurofibromas in Adults With Neurofibromatosis Type 1
NCT04941027 ·Status: COMPLETED
-
Psychosocial Impact of Disclosing Cancer Predisposition Genetic Testing Results During Childhood
NCT04848142 ·Status: COMPLETED
-
Genetic Analysis of Familial Brain Aneurysms
NCT00011856 ·Status: COMPLETED
-
Genetics of Spina Bifida and Anencephaly
NCT00636233 ·Status: COMPLETED
-
Modifying Genes in Neurofibromatosis 1
NCT01650142 ·Status: UNKNOWN
-
Neonatal Seizure Registry, GEnetics of Post-Neonatal Epilepsy
NCT05361070 ·Status: ACTIVE_NOT_RECRUITING
-
Genetics of Epilepsy and Related Disorders
NCT01858285 ·Status: RECRUITING
-
Genetic Study of Familial Epilepsy
NCT00006059 ·Status: COMPLETED
-
Genetic and Physical Study of Childhood Nerve and Muscle Disorders
NCT01568658 ·Status: ACTIVE_NOT_RECRUITING
-
Gliogene: Brain Tumor Linkage Study
NCT00418899 ·Status: UNKNOWN
-
Studies of Autistic Patients: Gene Networks and Clinical Subtypes
NCT01092208 ·Status: TERMINATED
-
Genetics of Endocrine Tumours - Familial Isolated Pituitary Adenoma - FIPA
NCT00461188 ·Status: RECRUITING
-
A Study of the Genetic Analysis of Brain Disorders
NCT00645645 ·Status: COMPLETED
-
Study of Clinical and Molecular Manifestations of Genetic Disorders
NCT00001466 ·Status: COMPLETED
-
Genetic Etiology in Patients With Cerebral Palsy
NCT05123768 ·Status: COMPLETED
-
Study of Genetic Risk Factors for Spina Bifida and Anencephaly
NCT00031122 ·Status: UNKNOWN
-
Genetic and Blood Biomarkers in Neurological and Neuromuscular Diseases
NCT02780531 ·Status: COMPLETED
-
Genetic and Metabolic Disease in Children
NCT02650622 ·Status: RECRUITING
-
Genome-wide Analysis of Single Nucleotide Polymorphisms of Brain Arteriovenous Malformations and Cerebral Aneurysm
NCT01801488 ·Status: TERMINATED
-
Somatic Mosaicism in Twins Discordant for Childhood Cancer
NCT06054295 ·Status: RECRUITING
-
Genetic Basis of Hemangiomas
NCT00466375 ·Status: TERMINATED
-
Genetic Risk Stratification of Pediatric Skin Lesions
NCT05418959 ·Status: ENROLLING_BY_INVITATION ·Phase: PHASE1
-
Clinical, Genetic, and Epidemiologic Study of Children and Adults With RASopathies
NCT04888936 ·Status: RECRUITING
-
Prevalence of Pituitary Incidentaloma in Relatives of Patients With Pituitary Adenoma
NCT00598949 ·Status: UNKNOWN