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The Effect of Coffee on the Absorption of Thyroid Hormone in Patients With Thyroid Carcinoma

NCT01707056 · Status: WITHDRAWN · Phase: NA · Type: INTERVENTIONAL

Last updated 2021-02-17

No results posted yet for this study

Summary

The purpose of this study is to evaluate whether taking thyroid hormone medication with beverages other than water, decreases absorption of the medication by the intestine. Specifically we are interested in whether coffee, coffee with milk, or black tea affects how thyroid medication is absorbed by the body. Previous studies have suggested that taking thyroid hormone with coffee may interfere with the ability to absorb thyroid medicine. Given that many patients take their thyroid medicine with beverages other than water, and specifically with coffee or tea, understanding whether and how much coffee or tea may decrease thyroid hormone absorption is important for clinical practice.

This study will help determine the safest and most effective way for adults to take their thyroid medication and will guide medical practitioners in how to counsel their patients when they prescribe thyroid hormone.

Conditions

Interventions

OTHER

Black Coffee

Taking Synthroid with 12 ounces of black coffee for 6 weeks.

OTHER

Coffee with Milk

Taking Synthroid with 12 ounces of black coffee and 2 ounces of 2% milk for a period of 6 weeks.

OTHER

Black Tea

Taking Synthroid with 12 ounces of black tea for a period of 6 weeks.

OTHER

Water

Taking Synthroid with water for a period of 6 weeks.

Sponsors & Collaborators

  • Georgetown University

    collaborator OTHER

  • Medstar Health Research Institute

    lead OTHER

Principal Investigators

  • Dorota Krajewski, MD · MedStar Health

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2012-09-30
Primary Completion
2015-06-30
Completion
2016-06-30

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01707056 on ClinicalTrials.gov