Cross-Sectional Iloperidone IVGTT
NCT01686815 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 37
Last updated 2019-03-12
Summary
This study aims to utilize state of the art procedures such as the frequently sampled intravenous glucose tolerance test (FSIVGTT), Bergman's Minimal Model Analysis, lipoprotein analysis, and DEXA scans to demonstrate that a newer agent, iloperidone, is devoid of the metabolic abnormalities associated with other atypical antipsychotic treatments, namely olanzapine and risperidone, and offers an advantage over these other agents.
Conditions
- Schizophrenia
- Serious Mental Illness
- Metabolic Syndrome
- Insulin Resistance
- Glucose Metabolism
Sponsors & Collaborators
- collaborator INDUSTRY
-
Massachusetts General Hospital
lead OTHER
Principal Investigators
-
Maurizio Fava, MD · Massachusetts General Hospital
Eligibility
- Min Age
- 18 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2012-10-31
- Primary Completion
- 2016-05-31
- Completion
- 2016-05-31
Countries
- United States
Study Locations
More Related Trials
-
Reducing Weight Gain and Improving Metabolic Function in Children Being Treated With Antipsychotics
NCT00806234 ·Status: COMPLETED ·Phase: PHASE4
-
Effect of Ziprasidone on Glucose & Plasma Lipids in Diabetes (II) and Schizophrenia or Schizoaffective Disorder
NCT00395031 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Effects of Adjunctive Metformin on Metabolic Profiles in Clozapine-treated Schizophrenic Patients
NCT01300637 ·Status: UNKNOWN ·Phase: NA
-
Monitoring and Management for Metabolic Side Effects of Antipsychotics
NCT01875861 ·Status: COMPLETED ·Phase: NA
-
Semaglutide in Comorbid Schizophrenia Spectrum Disorder and Obesity
NCT05333003 ·Status: RECRUITING ·Phase: NA
-
Acute Impact of Intramuscular (IM) Aripiprazole and Olanzapine on Insulin Resistance in High Risk Prediabetics
NCT01411930 ·Status: COMPLETED ·Phase: PHASE4
-
Metformin for the Prevention of the Metabolic Side-effects of Zyprexa
NCT00682448 ·Status: COMPLETED ·Phase: PHASE4
-
Metformin for Treatment of Antipsychotic-induced Dyslipidemia
NCT01778244 ·Status: COMPLETED ·Phase: PHASE4
-
Metformin Alleviates Abnormal Glucose Metabolism Induced by Statins in Schizophrenia Patients
NCT07045142 ·Status: RECRUITING ·Phase: PHASE3
-
Anti-psychotic Medication (New Use) Weight Loss Study
NCT01272752 ·Status: WITHDRAWN ·Phase: PHASE2
-
Diabetes in Neuropsychiatric Disorders
NCT00446992 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Metabolic Effects of Antipsychotics in Children
NCT00205699 ·Status: COMPLETED ·Phase: PHASE4
-
Alleviating the Metabolic Side Effects of Antipsychotic Medications
NCT01567124 ·Status: WITHDRAWN ·Phase: PHASE4
-
Does a GLP-1 Receptor Agonist Change Glucose Tolerance in Antipsychotic-treated Patients?
NCT01845259 ·Status: UNKNOWN ·Phase: PHASE2
-
One-Year Trial Of Oral Ziprasidone In Patients With Metabolic Syndrome
NCT00748566 ·Status: TERMINATED ·Phase: PHASE4
-
Does GLP-1RA Prevent Deterioration of Metabolic State in Prediabetic and Diabetic Patients Treated With Antipsychotic Medication?
NCT04892199 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE4
-
Topiramate vs Metformin on Cardio-Metabolic Profile in Schizophrenia on Atypical Antipsychotics
NCT05663749 ·Status: COMPLETED ·Phase: PHASE4
-
Examining the Effects of Antipsychotic Medications on Insulin Sensitivity
NCT00895921 ·Status: COMPLETED ·Phase: PHASE4
-
MEtformin and Lorcaserin for WeighT Loss in Schizophrenia
NCT02796144 ·Status: TERMINATED ·Phase: PHASE4
-
Changes in Adiposity, Metabolic Measures From Atypicals to Aripiprazole
NCT00205660 ·Status: COMPLETED ·Phase: PHASE4
-
Metformin for Weight Loss in Schizophrenia
NCT01177709 ·Status: TERMINATED ·Phase: NA
-
β-Cell Function in Schizophrenic Subjects on Atypical Antipsychotic drugS
NCT00528359 ·Status: COMPLETED
-
Pfizer/IVGTT/Ziprasidone/Olanzapine
NCT00205725 ·Status: COMPLETED ·Phase: NA
-
Effects of Antipsychotics on Brain Insulin Action in Females
NCT06251635 ·Status: RECRUITING ·Phase: NA
-
Improving Metabolic Parameters of Antipsychotic Child Treatment With Ziprasidone, Aripiprazole, and Clozapine
NCT00617058 ·Status: TERMINATED ·Phase: PHASE2