The Assessment and Treatment of Balance Impairment Using Virtual Reality (VR) in Panic Disorder Patients

Summary

Hypotheses

The investigators hypothesize that among individuals who suffer from panic disorder there is higher incidence of co-morbid balance impairment than in the healthy population.

The investigators hypothesize that the treatment of panic disorder, through the treatment of co-morbid balance impairment using virtual reality (VR) exposure therapy environment, is more effective than the exposure to still pictures from the same scene in VR without balance challenge or comparing to standard cognitive behavioral therapy (CBT) for the treatment of panic disorder.

Rationale

This research relies on previous studies, which have shown mutuality between anxiety and balance impairment, even if only sub-clinical. The VR-based training environment enables multi-sensorial stimulus in a dynamic interactively changing setting. With the addition of a cognitive task (dual task distracting the fear), the investigators can add cognitive load and therefore challenge the control of balance even more. Individuals who suffer from balance impairment avoid their exposure to many balance-challenging situations - a fact that may increase their anxiety. The investigators assume that a considerable number of PD individuals also experience balance control impairments - mostly subclinical ones. Moreover, balance impairment accompanies other psychiatric disorders, though not enough literature exists on the subject.

Conditions

• Panic Disorder
• Proprioceptive Disorders

Interventions

DEVICE

VR movie + balance challenge

Computer Assisted Rehabilitation Environment Integrated Reality System used for the challenge of balance control

DEVICE

still pictures from VR

Monitoring only still pictures from the VR scene in a loop, no balance challenge

BEHAVIORAL

Cognitive Behavioral Therapy

For the treatment of panic disorder

Sponsors & Collaborators

• Sheba Medical Center

  lead OTHER_GOV

Principal Investigators

• Asaf Caspi, MD · Sheba Medical Center

• Matti Mintz, PhD · Tel Aviv University

• Revital Amiaz, MD · Sheba Medical Center

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

TRIPLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Max Age

45 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2015-06-30

Primary Completion

2016-06-30

Completion

2016-09-30

Countries

• Israel

Study Locations