Evaluation of Heparin Rebound in Cardiac Surgery

NCT01675817 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 20

Last updated 2019-09-25

No results posted yet for this study

Summary

Recent work has shown that heparin rebound is common after cardiac surgery.

The exact doze of protamine required to neutralize heparin at the end of CPB is unknown. Besides, the precise doze of protamine to treat heparin rebound is also unknown. It is also unknown if precise titration of protamine perioperatively in cardiac surgery can influence transfusion requirements after cardiac surgery.

Conditions

  • Coagulation Delay

Sponsors & Collaborators

  • Academic Medical Organization of Southwestern Ontario

    collaborator OTHER
  • London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

    lead OTHER

Principal Investigators

  • Ravi Taneja, MD, FRCPC · London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

Eligibility

Min Age
18 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2011-04-30
Primary Completion
2013-03-31
Completion
2013-03-31

Countries

  • Canada

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01675817 on ClinicalTrials.gov