Evaluation of Heparin Rebound in Cardiac Surgery
NCT01675817 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 20
Last updated 2019-09-25
Summary
Recent work has shown that heparin rebound is common after cardiac surgery.
The exact doze of protamine required to neutralize heparin at the end of CPB is unknown. Besides, the precise doze of protamine to treat heparin rebound is also unknown. It is also unknown if precise titration of protamine perioperatively in cardiac surgery can influence transfusion requirements after cardiac surgery.
Conditions
- Coagulation Delay
Sponsors & Collaborators
-
Academic Medical Organization of Southwestern Ontario
collaborator OTHER -
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
lead OTHER
Principal Investigators
-
Ravi Taneja, MD, FRCPC · London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Eligibility
- Min Age
- 18 Years
- Max Age
- 90 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2011-04-30
- Primary Completion
- 2013-03-31
- Completion
- 2013-03-31
Countries
- Canada
Study Locations
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