Effects of Preoperative Physical Therapy in Patients With Lower Extremity Malignancy

Summary

This application proposes a prospective clinical trial to evaluate the impact of adding a focused physical therapy (PT) intervention to the preoperative regimen of individuals diagnosed with a malignancy of the lower extremity (LE). The primary aim will be to determine if individuals diagnosed with a malignancy of the LE can participate in a 10 week preoperative strengthening, stretching, and aerobic exercise regimen.

Conditions

• Osteosarcoma
• Ewing's Sarcoma
• Rhabdomyosarcoma
• Synovial Sarcoma
• Malignant Peripheral Nerve Sheath Sarcoma
• Malignant Fibrous Histiocytoma of the Bone
• Chondrosarcoma of the Bone

Interventions

OTHER

Endurance

Endurance exercise will consist of ambulating with assistive devices as needed, upper extremity (UE) ergometer, and/or playing the Wii.

OTHER

Strengthening

Strengthening exercises will involve both UE's and LE's. For UE's, bicep curls, triceps curls, shoulder flexion, and/or press-ups from the therapy mat or wheelchair will be included. For the LE's, bridging, long arc quads, hamstring curls, calf raises in standing, single LE squats, and/or dorsiflexion (DF) in supine will be performed on the uninvolved extremity.

OTHER

Stretching

Stretching will consist of ankle stretch into DF in supine or long sitting, hamstring stretch in supine with hip flexed to 90 degrees, and trunk extension in sitting.

OTHER

Home exercise program

All participants will be given a tailored home exercise program (HEP) including endurance exercises, strengthening, and stretching exercises to be completed on days they do not have PT. If the participants return home, they will be asked to complete the HEP at least 3 days per week. The physical therapist will contact the participant weekly to modify the HEP if necessary and determine compliance.

Sponsors & Collaborators

• Tennessee Physical Therapy Association

  collaborator UNKNOWN

• St. Jude Children's Research Hospital

  lead OTHER

Principal Investigators

• Angela M. Corr, PT, DPT · St. Jude Children's Research Hospital

Study Design

Allocation

NA

Purpose

SUPPORTIVE_CARE

Masking

NONE

Model

SINGLE_GROUP

Eligibility

Min Age

6 Years

Max Age

30 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2012-09-30

Primary Completion

2015-11-30

Completion

2015-11-30

Countries

• United States

Study Locations