Dovitinib in Neuroendocrine Tumors
NCT01635907 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 8
Last updated 2020-04-14
Summary
This study is being conducted to evaluate whether the investigational drug Dovitinib, can shrink or slow the growth of cancer in patients with certain types of neuroendocrine tumors. This study will also further evaluate the safety of this drug.
Conditions
- Advanced Metastatic Paraganglioma
- Advanced Metastatic Pheochromocytoma
- Recurrent Paraganglioma
- Recurrent Pheochromocytoma
- Unresectable Paraganglioma
- Unresectable Pheochromocytoma
Interventions
- DRUG
-
Dovitinib
Sponsors & Collaborators
-
Abramson Cancer Center at Penn Medicine
lead OTHER
Principal Investigators
-
Stephen Keefe, MD · Abramson Cancer Center at Penn Medicine
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2012-06-30
- Primary Completion
- 2016-03-31
- Completion
- 2016-04-11
Countries
- United States
Study Locations
More Related Trials
-
SC-002 in Small Cell Lung Cancer and Large Cell Neuroendocrine Carcinoma
NCT02500914 ·Status: TERMINATED ·Phase: PHASE1
-
Pembrolizumab for the Treatment of Recurrent High Grade Neuroendocrine Carcinoma
NCT03190213 ·Status: TERMINATED ·Phase: PHASE2
-
Nivolumab and Metformin Hydrochloride in Treating Patients With Stage III-IV Non-small Cell Lung Cancer That Cannot Be Removed by Surgery
NCT03048500 ·Status: UNKNOWN ·Phase: PHASE2
-
CI-1040 in Treating Patients With Advanced Breast, Colon, Pancreatic, or Non-Small Cell Lung Cancer
NCT00033384 ·Status: COMPLETED ·Phase: PHASE2
-
A Study Evaluating the Efficacy and the Safety of First-line Chemotherapy Combined With the Therapeutic Vaccine Named TG4010 and Nivolumab in Patients With Advanced Non-squamous Non-Small Cell Lung Cancer (NSCLC)
NCT03353675 ·Status: COMPLETED ·Phase: PHASE2
-
Durvalumab With Carboplatin and Etoposide Chemotherapy in Pulmonary Large-cell Neuroendocrine Carcinoma (LCNEC)
NCT06418087 ·Status: RECRUITING ·Phase: PHASE2
-
A Study of Gemcitabine-Carboplatin Plus Necitumumab (LY3012211) in Chemotherapy-Naïve Participants With Locally Advanced or Metastatic Squamous Non-Small Cell Lung Cancer (NSCLC)
NCT02941601 ·Status: WITHDRAWN ·Phase: PHASE2
-
A Phase II Study of Dacomitinib in Progressive Brain Metastases
NCT02047747 ·Status: TERMINATED ·Phase: PHASE2
-
Phase-II Study of Lu177DOTATOC in Adults With STTR(+)Pulmonary, Pheochromocytoma, Paraganglioma, Unknown Primary, Thymus NETs (PUTNET), or Any Other Non-.GEP-NET.
NCT04276597 ·Status: WITHDRAWN ·Phase: PHASE2
-
Comparing Dosing Intervals of Nivolumab or Pembrolizumab in Locally Advanced or Metastatic Cancers
NCT04295863 ·Status: RECRUITING ·Phase: PHASE1
-
A Study of 177Lu-DTPA-SC16.56 in People With Neuroendocrine Carcinomas of the Lung and Prostate
NCT06941480 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1
-
Docetaxel and Cisplatin With or Without Dimesna in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer
NCT00077311 ·Status: COMPLETED ·Phase: PHASE2
-
Phase II Trial of Doxorubicin and Bortezomib in Patients With Incurable Adenoid Cystic Carcinoma of the Head and Neck
NCT00581360 ·Status: COMPLETED ·Phase: PHASE2
-
S9806: Combination Chemotherapy in Treating Patients With Stage IIIB or Stage IV Non-small Cell Lung Cancer
NCT00003587 ·Status: COMPLETED ·Phase: PHASE2
-
Study to Investigate the Efficacy of Panitumumab in Platinum-resistant Advanced Head and Neck Squamous Cancer
NCT02643056 ·Status: COMPLETED ·Phase: PHASE2
-
Study of Dovitinib (TKI258) in Adenoid Cystic Carcinoma
NCT01524692 ·Status: COMPLETED ·Phase: PHASE2
-
Study of Carotuximab (TRC105) Plus Nivolumab in Patients With Metastatic NSCLC
NCT03181308 ·Status: COMPLETED ·Phase: PHASE1
-
Phase II Study of Abraxane and Gemicitabine in Patients With Advanced Adenocarcinoma Non-Small Cell Lung Cancer Progressing After First-Line Platinum-Based Chemotherapy
NCT02303977 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of Necitumumab and Chemotherapy in Participants With Stage IV Squamous Non-Small Cell Lung Cancer
NCT01769391 ·Status: COMPLETED ·Phase: PHASE2
-
A Multicenter Phase 2 Study of CI-1040 in Patients With Advanced Nonsmall-Cell Lung, Breast, Colon and Pancreatic Cancer
NCT00034827 ·Status: COMPLETED ·Phase: PHASE2
-
Targeted Therapy With CDK4/6 Inhibitors in Chemo-Refractory, Rb Wild-Type Extensive SCLC
NCT04010357 ·Status: COMPLETED ·Phase: PHASE2
-
Safety of Adding IMO-2055 to Erlotinib + Bevacizumab in 2nd Line Treatment for Patients With NSCLC
NCT00633529 ·Status: COMPLETED ·Phase: PHASE1
-
Diclofenac for the Treatment of Patients With Metastatic Non-small Cell Lung Cancer on Single Agent Immunotherapy
NCT06731270 ·Status: RECRUITING ·Phase: PHASE2
-
Nivolumab in Combination With Ipilimumab (Part 1); Nivolumab Plus Ipilimumab in Combination With Chemotherapy (Part 2) as First Line Therapy in Stage IV Non-Small Cell Lung Cancer
NCT02659059 ·Status: COMPLETED ·Phase: PHASE2
-
Nivolumab With Ipilimumab in Subjects With Neuroendocrine Tumors
NCT03420521 ·Status: TERMINATED ·Phase: PHASE2