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The Effects of Daptomycin and Cytokines Production in Comparison With Vancomycin

NCT01626560 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 20

Last updated 2015-03-20

No results posted yet for this study

Summary

Primary: To determine the influence of daptomycin on inflammatory cytokine (IL-1, TNF and IL-6) for the treatment of complicated cellulitis/erysipela compared with alternative treatment (vancomycin or oxacillin). Secondary: To evaluate the clinical outcome of both groups according to levels of the cytokines evaluated.

Conditions

  • Cellulitis

Interventions

DRUG

Daptomycin

daptomycin 4-6mg/kg qd 10 - 14 days

DRUG

Vancomycin

Vancomycin 1g q12h 10 - 14 days

Sponsors & Collaborators

  • Hospital Universitario Evangelico de Curitiba

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2012-07-31
Primary Completion
2015-03-31
Completion
2015-03-31

Countries

  • Brazil

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01626560 on ClinicalTrials.gov