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RCT to Investigate if Prophylactic Antibiotics Prevent Further Episodes of Cellulitis (Erysipelas) of the Leg

NCT00552799 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 274

Last updated 2012-07-24

No results posted yet for this study

Summary

To assess whether a period of prophylactic penicillin after an episode of cellulitis of the leg reduces the risk of repeat episodes. Participants are randomised to receive 12 months of prophylaxis (penicillin VK 250mg b.d. or placebo). The PATCH I study will recruit only patients with recurrent disease.

Conditions

  • Cellulitis/Erysipelas of the Leg

Interventions

DRUG

Penicillin VK

Biconcave tablet 250mg oral, b.d.

OTHER

placebo

biconcave tablet matching active comparator as much as possible in size and shape

Sponsors & Collaborators

  • Action Medical Research

    collaborator OTHER

  • UK Dermatology Clinical Trials Network

    collaborator NETWORK

  • University of Nottingham

    lead OTHER

Principal Investigators

  • Hywel Williams, Professor · University of Nottingham

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
16 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2006-07-31
Primary Completion
2011-11-30
Completion
2011-11-30

Countries

  • Ireland
  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00552799 on ClinicalTrials.gov