Project RETAIN: Providing Integrated Care for HIV-Infected Crack Cocaine Users

Summary

This study will evaluate the efficacy of an integrated "Retention Clinic" in achieving virologic suppression among HIV-infected cocaine (including crack) users by using a two-group randomized, prospective trial. A total of 360 HIV-infected individuals who report cocaine (including crack) use will be randomized across study sites. The primary hypothesis is that more participants randomized to the "Retention Clinic" will have undetectable viral load than will participants randomized to the treatment as usual group.

Conditions

• HIV
• AIDS
• Substance Abuse

Interventions

BEHAVIORAL

Retention Clinic

The central components of the Retention Clinic will include: Primary HIV Care; Patient Navigator services (including Informational support, Educational information, Motivational/Emotional support, Skill Building activities); Mental Health Services; and On-Site Substance Abuse Treatment (including Motivational Enhancement Therapy and Cognitive Behavioral Therapy).

Sponsors & Collaborators

• Emory University

  collaborator OTHER

• University of Miami

  collaborator OTHER

• The Village South

  collaborator OTHER

• Grady Health System

  collaborator OTHER

• Jackson Health System

  collaborator OTHER

• National Institute on Drug Abuse (NIDA)

  collaborator NIH

• Columbia University

  lead OTHER

Principal Investigators

• Lisa R. Metsch, Ph.D. · Columbia University

• Carlos del Rio, M.D. · Emory University

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2013-01-31

Primary Completion

2017-12-31

Completion

2021-03-12

Countries

• United States

Study Locations