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Effect of Single Doses of YF476 on Stomach Acidity

NCT01601418 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 12

Last updated 2012-05-18

No results posted yet for this study

Summary

The objective of the study was to assess the effect of a range of single oral doses of YF476 on pentagastrin-induced gastric acid output in healthy volunteers

Conditions

  • Hypergastrinaemia

Interventions

DRUG

YF476

Each subject took one capsule of YF476 (1, 5, 25 or 100 mg) or placebo on five separate occasions. Each capsule was taken with water 150 mL.

DRUG

Placebo

Each subject took one capsule of YF476 (1, 5, 25 or 100 mg) or placebo on five separate occasions. Each capsule was taken with water 150 mL.

Sponsors & Collaborators

  • James Black Foundation

    collaborator UNKNOWN

  • Trio Medicines Ltd.

    lead INDUSTRY

Principal Investigators

  • Malcolm Boyce · Trio Medicines Limited

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
45 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2001-10-31
Primary Completion
2002-01-31
Completion
2002-01-31

Countries

  • United Kingdom

Study Locations

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Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01601418 on ClinicalTrials.gov