F18-FLT PET/CT as a Tool for Assessment of Myeloablative Treatment in Patients With Acute Myeloid Leucemia(AML)
NCT01592266 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 10
Last updated 2012-05-07
Summary
PET/CT is reliable tool in evaluation of treatment response in number cancers. F18-FLT is a precursor of DNA with high uptake in the bone marrow as a part of normal biodistribution. Highly increased uptake of this radiopharmaceutical was shown in a number of hematologic disease either in bone marrow or extramedullary.
F18-FLT PET/CT can provide a tool for whole body assessment of activity in bone marrow as well as early estimation of treatment efficacy or lack of it. In addition, this noninvasive study can replace bone marrow biopsy and predict response vs. non response to therapy.
Conditions
- Acute Myeloid Leucemia
Sponsors & Collaborators
-
Hadassah Medical Organization
lead OTHER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2012-10-31
- Primary Completion
- 2013-10-31
Countries
- Israel
Study Locations
More Related Trials
-
PET/MRI, 18F-FDG PET/CT and Whole Body MRI in Finding Extramedullary Myeloid Leukemia in Patients With Newly Diagnosed Acute Myeloid Leukemia
NCT02390635 ·Status: RECRUITING ·Phase: PHASE1
-
Imaging of T-cell Activation With [18F]F-AraG in Advanced Non Small Cell Lung Cancer
NCT04726215 ·Status: UNKNOWN ·Phase: PHASE2
-
Early Response Assessment of Induction Chemotherapy in Acute Myeloid Leukemia Patients Using F-18 FLT PET/CT
NCT02103530 ·Status: COMPLETED ·Phase: NA
-
[18F]FLT PET/CT in Rb+ Metastatic Breast Cancer
NCT02608216 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
FLT-PET as an Imaging Biomarker With Temsirolimus, Topotecan, and Bortezomib
NCT01143779 ·Status: COMPLETED ·Phase: PHASE1
-
FLT-PET/MRI for Early Response Monitoring to Novel Cancer Therapeutic Agents
NCT02055586 ·Status: COMPLETED
-
FLT-PET in Predicting Response to Chemotherapy in Patients With Advanced Malignancies
NCT00880074 ·Status: COMPLETED ·Phase: PHASE1
-
Comparison of F-18 FDG and C-11 Acetate PET in Multiple Myeloma
NCT03262389 ·Status: COMPLETED ·Phase: PHASE2
-
A Study Using [18F]F AraG PET to Evaluate Response to Checkpoint Inhibitor Therapy(CkIT) in Patients With Solid Tumors
NCT04260256 ·Status: TERMINATED ·Phase: PHASE2
-
3'-Deoxy-3'-[18F] Fluorothymidine PET Imaging in Patients With Cancer
NCT00935090 ·Status: RECRUITING
-
18F-FLT (PET/CT) in Prefibrotic/Early Primary Myelofibrosis and Essential Thrombocythemia
NCT03116542 ·Status: UNKNOWN ·Phase: NA
-
18F-FLT (PET/CT) in Pediatrics With Myeloproliferative Neoplasms
NCT03121599 ·Status: TERMINATED ·Phase: NA
-
18F-FLT PET Imaging in Patients With Advanced Melanoma
NCT02891616 ·Status: TERMINATED ·Phase: PHASE1
-
Immune Checkpoint Blockade Therapy Using 18F-FLT PET/CT
NCT04271436 ·Status: WITHDRAWN ·Phase: PHASE2
-
Imaging of Primary or Recurrent Breast Cancer With 18F-FluorThanatrace PET/CT
NCT03846167 ·Status: ACTIVE_NOT_RECRUITING
-
An Efficacy and Safety Study to Assess [18F]-ML-10 in Detecting Response of Tumors to Chemotherapy and Radiation
NCT01260480 ·Status: UNKNOWN ·Phase: PHASE2
-
PET Tracer Based FDG Signal for Predicting Prognosis in Acute Myeloid Leukemia
NCT05919199 ·Status: UNKNOWN
-
Evaluation of the Efficacy and Safety of [18F]-ML-10, as a PET Imaging Radiotracer, in Early Detection of Response of Brain Metastases of Solid Tumors to Radiation Therapy.
NCT00805636 ·Status: UNKNOWN ·Phase: PHASE2
-
Evaluation of PET 18F-Fludarabine for the Initial Assessment and End-treatment of Symptomatic Multiple Myeloma Patients
NCT03832127 ·Status: RECRUITING ·Phase: PHASE1
-
[18F]Fluoroestradiol-PET/CT Imaging of Invasive Lobular Carcinoma
NCT04252859 ·Status: TERMINATED ·Phase: PHASE2
-
Value of FLT PET/CT in Radium-223 Therapy of mCRPC Patients
NCT03011749 ·Status: TERMINATED ·Phase: NA
-
PET Imaging of Solid Tumors Using 124I-Humanized 3F8: A Pilot Study
NCT02307630 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
FLT-PET/CT vs FDG-PET/CT for Therapy Monitoring of Diffuse Large B-cell Lymphoma
NCT01410630 ·Status: COMPLETED
-
Molecular Imaging to Capture Disease Heterogeneity in Acute Myeloid Leukemia
NCT02682732 ·Status: UNKNOWN ·Phase: NA
-
A Pilot Study of F-18 Paclitaxel (FPAC) PET for Evaluating Drug Delivery of Solid Tumors in Breast, Lung, Renal, and Adrenal Cancers
NCT01086696 ·Status: TERMINATED ·Phase: EARLY_PHASE1