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Early Versus Delayed Cord Clamping at Term: Neurodevelopmental Outcomes in Swedish Infants at 4 Years of Age

NCT01581489 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 263

Last updated 2023-06-22

No results posted yet for this study

Summary

Delayed clamping of the umbilical cord might prevent or slow the onset of iron deficiency by increasing the infant's iron endowment at birth. Compared to early clamping, a delay in clamping in clamping of around 2-3 min provides an additional 25-40 mL of blood per kg of bodyweight to the newborn infant.

The results of previous intervention studies on delayed clamping are mixed, and few have followed the infants beyond the perinatal period. All longer follow up studies have been performed in low income countries except for the investigators earlier study, showing less iron deficiency and improved iron stores after delayed cord clamping at 4 months of age.

The main objective of the current study is to assess whether the time of cord clamping affects neurodevelopment at 4 years of age in a large sample of full-term, Swedish infants. The investigators hypothesis is that as delayed cord clamping improves iron stores at 4 months, this could affect the child's development positively.

Conditions

Interventions

PROCEDURE

Time to clamping of the umbilical cord after delivery

The time after delivery of the newborn until the midwife stops the circulation in the umbilical cord with a clamp.

Sponsors & Collaborators

  • Umeå University

    collaborator OTHER

  • Halmstad County Hospital

    collaborator OTHER

  • County Council of Halland, Sweden

    collaborator OTHER_GOV

  • Uppsala University

    lead OTHER

Principal Investigators

  • Ola Andersson, MD · Hospital of Halland, Halmstad

  • Barbro Lindquist, PhD · Hospital of Halland, Halmstad

  • Lena Hellström-Westas, Professor · Uppsala University

Eligibility

Min Age
48 Months
Max Age
51 Months
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2012-04-30
Primary Completion
2013-08-31
Completion
2013-08-31

Countries

  • Sweden

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01581489 on ClinicalTrials.gov